We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310099PMC
http://dx.doi.org/10.3201/eid1801.110556DOI Listing

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