The study of fatigue is an important tool for diagnostics of disease, sports, ergonomics and robotics areas. This work deals with the analysis of sEMG most important fatigue muscle indicators with use of signal processing in isometric and isotonic tasks with the propose of standardizing fatigue protocol to select the data acquisition and processing with diagnostic proposes. As a result, the slope of the RMS, ARV and MNF indicators were successful to describe the fatigue behavior expected. Whereas that, MDF and AIF indicators failed in the description of fatigue. Similarly, the use of a constant load for sEMG data acquisition was the best strategy in both tasks.
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http://dx.doi.org/10.1109/IEMBS.2011.6091810 | DOI Listing |
SAGE Open Med
January 2025
Tufts University School of Medicine, Boston, MA, USA.
Objective: This study utilized a sample of trangender, nonbinary, and gender-diverse (TGD) patients to build on emerging literature that suggests that hypermobile Ehlers-Danlos syndrome may be overrepresented in TGD populations. The objective of this retrospective chart review was to determine the prevalence of hypermobile Ehlers-Danlos syndrome syndrome at a gender-affirming primary care clinic.
Methods: A retrospective chart review of medical records was conducted with records between May 2021 and June 2024.
Front Pharmacol
January 2025
The First Department of Specialty Medicine, Inner Mongolia Corps Hospital of The Chinese People's Armed Police Force, Hohhot, China.
Introduction: Eculizumab is a C5 complement inhibitor approved by the FDA for the targeted treatment of four rare diseases, paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), generalized myasthenia gravis (gMG), and aquaporin-4 immunoglobulin G-positive optic neuromyelitis optica spectrum disorders (AQP4-IgG+NMOSD). The current study was conducted to assess real-world adverse events (AEs) associated with eculizumab through data mining of the FDA Adverse Event Reporting System (FAERS).
Methods: Disproportionality analyses, including Reporting Ratio Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Multi-Item Gamma Poisson Shrinker (MGPS) algorithms were used to quantify the signals of eculizumab-associated AEs.
Explor Neuroprotective Ther
April 2024
School of Nursing, University of Michigan, Ann Arbor, MI 48109, USA.
Aim: Childhood stressors can increase adult stress perception and may accumulate over the lifespan to impact symptoms of multiple sclerosis (MS). Growing evidence links childhood stressors (e.g.
View Article and Find Full Text PDFCrit Care Explor
January 2025
Department of Neonatal and Pediatric Intensive Care, Division of Pediatric Intensive Care, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.
Objectives: The COVID-19 pandemic gave rise to uncertainty concerning potential sequelae related to a severe acute respiratory syndrome coronavirus 2 infection. This landscape is currently unfolding with studies reporting sequelae on various domains (physical, cognitive, and psychosocial), although most studies focus on adults or only one domain. We sought to investigate concurrent sequelae on multiple domains 1 year after PICU admission for Multisystem Inflammatory Syndrome in Children (MIS-C).
View Article and Find Full Text PDFHeliyon
January 2025
University of Coimbra, CEMMPRE, ARISE, Department of Mechanical Engineering, Rua Luís Reis Santos, 3030-788, Coimbra, Portugal.
Recent advancements in aerospace industry demand intricate aero-engine parts, leading to the increased use of titanium alloys, particularly Ti-17, due to its high strength, thermal stability, and corrosion resistance. However, its low thermal conductivity and tool wear tendency pose significant machining challenges, impacting surface integrity, fatigue life, and overall component performance. This study investigates the Wire Electrical Discharge Cutting (WEDC) process, revealing that the mechanism behind improved surface integrity lies in the controlled thermal input, which minimizes phase transformations and reduces residual stresses.
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