The development of minimally invasive surgical techniques using magnetism is expanding. Our research group is exploring catheter steering using the gradient field of a modified clinical Magnetic Resonance Imaging (MRI) system. This paper focuses on the upgrade of the MRI testing platform towards an integrated system allowing for in vitro and in vivo experiments. The expected steering capabilities of the platform are evaluated through experimental tests, and catheter tracking is adapted accordingly while being tested for potential medical interventions.
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http://dx.doi.org/10.1109/IEMBS.2011.6091333 | DOI Listing |
Mol Pharm
January 2025
Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji 133002, China.
The morbidity and mortality rates of hepatocellular carcinoma (HCC) are high and continue to increase. The antitumor effects of single therapies are limited because of tumor heterogeneity and drug resistance, and the lack of real-time monitoring of tumor progression during the treatment process leads to poor therapeutic outcomes. Therefore, novel nanodelivery platforms combining tumor therapy and diagnosis have garnered extensive attention.
View Article and Find Full Text PDFHum Brain Mapp
December 2024
SEB Centre for Brain Resilience & Recovery, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Canada.
White matter hyperintensities (WMH) of presumed vascular origin are a magnetic resonance imaging (MRI)-based biomarker of cerebral small vessel disease (CSVD). WMH are associated with cognitive decline and increased risk of stroke and dementia, and are commonly observed in aging, vascular cognitive impairment, and neurodegenerative diseases. The reliable and rapid measurement of WMH in large-scale multisite clinical studies with heterogeneous patient populations remains challenging, where the diversity of imaging characteristics across studies adds additional complexity to this task.
View Article and Find Full Text PDFQuant Imaging Med Surg
December 2024
Program for Advanced Musculoskeletal Imaging, Cleveland Clinic, Cleveland, OH, USA.
Background: Dixon-based magnetic resonance imaging (MRI) intramuscular proton density fat fraction (PDFF) is a potentially useful imaging biomarker of muscle quality. However, multi-vendor, multi-site reproducibility of intramuscular PDFF quantification, required for large clinical studies, can be strongly dependent on acquisition and processing. The purpose of this study was (I) to develop a 6-point Dixon MRI-based acquisition and processing technique for reproducible multi-vendor, multi-site quantification of thigh intramuscular PDFF; and (II) to evaluate the ability of the technique to detect differences in thigh muscle status between operated .
View Article and Find Full Text PDFDigit Health
December 2024
School of Computer Science & Engineering (SCOPE), VIT-AP University, Amaravati, Andhra Pradesh, India.
Objective: Brain tumors are abnormal growths of brain cells that are typically diagnosed via magnetic resonance imaging (MRI), which helps to discriminate between malignant and benign tumors. Using MRI image analysis, tumor sites have been identified and classified into four distinct tumor categories: meningioma, glioma, not tumor, and pituitary. If a brain tumor is not detected in its early stages, it could progress to a severe level or cause death.
View Article and Find Full Text PDFJ Alzheimers Dis
December 2024
Hurvitz Brain Sciences, Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada.
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