Cataract remains a leading cause for blindness worldwide. Cataract diagnosis via human grading is subjective and time-consuming. Several methods of automatic grading are currently available, but each of them suffers from some drawbacks. In this paper, a new approach for automatic detection based on texture and intensity analysis is proposed to address the problems of existing methods and improve the performance from three aspects, namely ROI detection, lens mask generation and opacity detection. In the detection method, image clipping and texture analysis are applied to overcome the over-detection problem for clear lens images and global thresholding is exploited to solve the under-detection problem for severe cataract images. The proposed method is tested on 725 retro-illumination lens images randomly selected from a database of a community study. Experiments show improved performance compared with the state-of-the-art method.
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http://dx.doi.org/10.1109/IEMBS.2011.6091249 | DOI Listing |
Ophthalmic Physiol Opt
January 2025
Robert O Curle Ophthalmology Suite, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK.
Purpose: To determine whether imaging features derived from fundus photographs contain 3D eye shape information beyond that available from spherical equivalent refraction (SER).
Methods: We analysed 99 eyes of 68 normal adults in the UK Biobank. An ellipsoid was fitted to the entire volume of each posterior eye (vitreous chamber without the lens)-segmented from magnetic resonance imaging of the brain.
Micromachines (Basel)
January 2025
Department of Chemical and Biological Sciences, Faculty of Science, Japan Women's University, 2-8-1 Mejirodai, Bunkyo, Tokyo 112-8681, Japan.
Microfluidic-based cell-stretching devices are vital for studying the molecular pathways involved in cellular responses to mechanobiological processes. Accurate evaluation of these responses requires detailed observation of cells cultured in this cell-stretching device. This study aimed to develop a method for preparing microscope slides to enable high-magnification imaging of cells in these devices.
View Article and Find Full Text PDFBeijing Da Xue Xue Bao Yi Xue Ban
February 2025
Institute of Medical Technology, Peking University Health Science Center, Beijing 100191, China.
Objective: To quantitatively evaluate the accuracy of data obtained from liquid-interference surfaces using an intraoral 3D scanner (IOS) integrated with a compressed airflow system, so as to provide clinical proof of accuracy for the application of the compressed airflow system-based scanning head in improving data quality on liquid-interference surfaces.
Methods: The study selected a standard model as the scanning object, adhering to the "YY/T 1818-2022 Dental Science Intraoral Digital Impression Scanner" guidelines, a standard that defined parameters for intraoral scanning. To establish a baseline for accuracy, the ATOS Q 12M scanner, known for its high precision, was used to generate true reference values.
J Cataract Refract Surg
January 2025
Kepler University Hospital, University Clinic for Ophthalmology and Optometry.
Purpose: To comprehensively evaluate the tilt of the crystalline lens in phakic eyes and its relationship with optical biometry parameters.
Setting: The retrospective analysis was conducted at the Department for Ophthalmology and Optometry, Kepler University Clinic in Linz, Austria.
Design: Lens tilt assessment was performed through a combined analysis of optical biometry (IOL Master 700) and anterior segment optical coherence tomography (AS-OCT) data to understand its relationship.
Ocul Immunol Inflamm
January 2025
Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
Purpose: To observe the changes in the axial length (AL) in patients of acute retinal necrosis (ARN) undergoing vitrectomy and investigate the correlated factors.
Methods: Retrospective case series. Patients diagnosed as ARN undergoing vitrectomy with silicone oil (SO) tamponade, and with attached retina more than one year after silicone oil removal (SOR) were included.
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