In this study, an automated algorithm was developed to identify the arrhythmic gastric slow wave activity that was recorded using high-resolution mapping technique. The raw signals were processed with a Savitzky-Golay filter, and the slow wave activation times were identified using a threshold-varying method and grouped using a region-growing method. Slow wave amplitudes and velocities were calculated for all cycles. Arrhythmic events were identified when the orientation of a slow wave at an electrode exceeded the 95% confidence interval of the averaged orientation of several normal cycles. A second selection criterion was further developed to identify the arrhythmic events by an anisotropy ratio. In both pig and human studies, arrhythmias were associated with the emergence of circumferential velocity components and higher amplitudes.
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http://dx.doi.org/10.1109/IEMBS.2011.6091092 | DOI Listing |
ACS Photonics
January 2025
Institute of Electronic Structure and Laser, Foundation for Research and Technology-Hellas (FORTH-IESL), GR-70013 Heraklion, Crete, Greece.
THz metamaterials present unique opportunities for next-generation technologies and applications as they can fill the "THz gap" originating from the weak response of natural materials in this regime, providing a variety of novel or advanced electromagnetic wave control components and systems. Here, we propose a novel metamaterial design made of three-dimensional, metallic, "cactus-like" meta-atoms, showing electromagnetically induced transparency (EIT) and enhanced refractive index sensing performance at low THz frequencies. Following a detailed theoretical analysis, the structure is realized experimentally using multiphoton polymerization and electroless silver plating.
View Article and Find Full Text PDFBrain Behav
January 2025
Department of Neurology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Background And Objectives: Guillain-Barré syndrome (GBS), an acute inflammatory disorder of the peripheral nervous system, is characterized by muscle weakness and paralysis. Prompt identification of patients at a high risk of poor outcomes is crucial for timely intervention. In this study, we combined clinical data with nerve conduction study and electromyography data to identify the predictors of GBS outcomes.
View Article and Find Full Text PDFFront Aging Neurosci
January 2025
Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Objectives: This study seeks to delineate the sleep architecture characteristics in older adults with short-term insomnia and mild cognitive impairment (MCI) and to explore their association with cognitive performance.
Methods: Ninety elderly individuals with short-term insomnia were enrolled and stratified into two cohorts based on their Montreal Cognitive Assessment (MoCA) scores: the Short-Term Insomnia Group (STID) comprising 35 participants and the Short-Term Insomnia with Cognitive Impairment Group (STID-MCI) with 55 participants. Demographic data, Pittsburgh Sleep Quality Index (PSQI), MoCA, Hamilton Depression Rating Scale (HAMD-17), Hamilton Anxiety Rating Scale (HAMA), and polysomnography (PSG) parameters were compared between groups.
Front Aging Neurosci
January 2025
Department of Neurology, University Hospital of Zurich, Zurich, Switzerland.
Introduction: Improving sleep in murine Alzheimer's disease (AD) is associated with reduced brain amyloidosis. However, the window of opportunity for successful sleep-targeted interventions, regarding the reduction in pathological hallmarks and related cognitive performance, remains poorly characterized.
Methods: Here, we enhanced slow-wave activity (SWA) during sleep via sodium oxybate (SO) oral administration for 2 weeks at early (6 months old) or moderately late (11 months old) disease stages in Tg2576 mice and evaluated resulting neuropathology and behavioral performance.
BMC Public Health
January 2025
Economic Research Unit, Indian Statistical Institute, Kolkata, India.
Background: Ever since the emergence of COVID-19 and its consequent spread across continents, engulfing both advanced and developing nations, COVID-19 vaccine was considered to be the main weapon to curb the spread of the virus. The COVID-19 vaccination program in India started after the first wave of infections (March - December 2020) had almost subsided.
Objective: In this work, the objective is to perform a state-wise analysis to assess the impact of vaccination in slowing down the spread of infections during the second COVID-19 wave (February - October 2021) in India.
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