In this paper, we propose an automated liver segmentation method to overcome the challenging issues of high degree of variations in liver shape / size and similar density distribution shared by the liver and its surrounding structures. To improve the performance of conventional statistical shape model for liver segmentation, in our method, the signed distance function is utilized so that the landmarks correspondence is not required when performing the principle component analysis. We improve the Chan-Vese model to bind the shape energy and local intensity feature to evolve the surface both globally and locally toward the closest shape driven by the PCA. In our experiments, 20 clinical CT studies were used for training and 25 clinical CT studies were used for validation. Our experimental results demonstrate that our method can achieve accurate and robust liver segmentation from both of low-contrast and high-contrast CT images.
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http://dx.doi.org/10.1109/IEMBS.2011.6090924 | DOI Listing |
J Inflamm Res
December 2024
Department of Colorectal Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310016, People's Republic of China.
Herein, we described a case of small bowel Crohn's disease with recurrent, unexplained fevers, pain in the right lower back, hip, and groin area over 20 months. The patient did not present any gastrointestinal symptoms and colonoscopy showed no abnormalities. Imaging revealed a liver abscess and multiple lesions with pneumatosis in the muscles of the right lower back region.
View Article and Find Full Text PDFJ Hepatocell Carcinoma
December 2024
Department of Radiology, the First Affiliated Hospital of AnHui Medical University, Hefei, Anhui Province, People's Republic of China.
Objective: To develop and validate a deep learning-based automatic segmentation model and combine with radiomics to predict post-TACE liver failure (PTLF) in hepatocellular carcinoma (HCC) patients.
Methods: This was a retrospective study enrolled 210 TACE-trated HCC patients. Automatic segmentation model based on nnU-Net neural network was developed to segment medical images and assessed by the Dice similarity coefficient (DSC).
Am J Physiol Gastrointest Liver Physiol
December 2024
Arizona College of Osteopathic Medicine, Midwestern University, Glendale, Arizona, 85308 USA.
The goal of this study was to determine whether the influence of high-fat high-sugar diet (Western diet) on intestinal function and health was reversible. We measured transepithelial short circuit current (Isc), across freshly isolated segments of jejunum from male C57Bl/6J mice randomly assigned to one of the following groups for the study duration: high-fat high-sugar diet for 24-weeks (HFHS), HFHS diet for 12-weeks then switched to standard chow and water for a further 12 weeks (Std), and lean controls (standard chow and water for 24-weeks). At the completion of the study, segments of jejunum were frozen for western blot determination of key proteins involved in secretory and absorptive functions, as well as senescence.
View Article and Find Full Text PDFJ Hepatol
December 2024
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea; Inocras Inc., San Diego, CA, USA. Electronic address:
Background & Aims: Various hepatocellular carcinoma (HCC) prediction models have been proposed for patients with chronic hepatitis B (CHB) using clinical variables. We aimed to develop an artificial intelligence (AI)-based HCC prediction model by incorporating imaging biomarkers derived from abdominal computed tomography (CT) images along with clinical variables.
Methods: An AI prediction model employing a gradient-boosting machine algorithm was developed utilizing imaging biomarkers extracted by DeepFore, a deep learning-based CT auto-segmentation software.
Eur Radiol
December 2024
Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Objective: To develop and compare machine learning models based on CT morphology features, serum biomarkers, and basic physical conditions to predict esophageal variceal bleeding.
Materials And Methods: Two hundred twenty-four cirrhotic patients with esophageal variceal bleeding and non-bleeding were included in the retrospective study. Clinical and serum biomarkers were used in our study.
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