Modeling the adaptive pathophysiology of essential hypertension.

Annu Int Conf IEEE Eng Med Biol Soc

Department of Bioengineering , University of California, San Diego, La Jolla, CA, USA.

Published: June 2012

This paper proposes an adaptive neuro-fuzzy model to study the pathophysiology of essential hypertension. Using diverse inputs such as risk factors, physical relations and medical interventions, and states that include both transient and resting states for key physiological variables (blood pressure, total peripheral resistance), it can roughly predict both real-time and long-term blood pressure change for a robust range of inputs. Although it was tuned using published population data, it can be applied to specific individuals to estimate the risks of hypertension with different life experience.

Download full-text PDF

Source
http://dx.doi.org/10.1109/IEMBS.2011.6090239DOI Listing

Publication Analysis

Top Keywords

pathophysiology essential
8
essential hypertension
8
blood pressure
8
modeling adaptive
4
adaptive pathophysiology
4
hypertension paper
4
paper proposes
4
proposes adaptive
4
adaptive neuro-fuzzy
4
neuro-fuzzy model
4

Similar Publications

Advances in lacrimal gland organoid development: Techniques and therapeutic applications.

Biomed Pharmacother

January 2025

Department of Stem Cell and Regenerative Biotechnology, School of Advanced Biotechnology, Molecular & Cellular Reprogramming Center, Institute of Advanced Regenerative Science, and Institute of Health, Aging & Society, Konkuk University, 120 Neungdong-ro Gwangjin-gu, Seoul 05029, Republic of Korea; R&D Team, StemExOne Co., Ltd., Seoul, Republic of Korea. Electronic address:

The human lacrimal gland (LG), located above the outer orbital region within the frontal bone socket, is essential in maintaining eye surface health and lubrication. It is firmly anchored to the orbital periosteum by the connective tissue, and it is vital for protecting and lubricating the eye by secreting lacrimal fluid. Disruption in the production, composition, or secretion of lacrimal fluid can lead to dry eye syndrome, a condition characterized by ocular discomfort and potential eye surface damage.

View Article and Find Full Text PDF

: Asymptomatic patellar tendon abnormality (APTA) is considered a precursor to patellar tendinopathy (PT), but its pathogenesis remains unclear, especially regarding changes in muscle coordination. Therefore, it is essential to explore the muscle synergy patterns in individuals with APTA. This study recorded sEMG data during stop-jump tasks in 8 APTA and 8 healthy amateur male basketball players in a simulated basketball game.

View Article and Find Full Text PDF

Emerging Deep Brain Stimulation Targets in the Cerebellum for Tremor.

Cerebellum

January 2025

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Deep brain stimulation (DBS) for essential tremor is remarkably effective, leading to over 80% reduction in standardized tremor ratings. However, for certain types of tremor, such as those accompanied by ataxia or dystonia, conventional DBS targets have shown poor efficacy. Various rationales for using cerebellar DBS stimulation to treat tremor have been advanced, but the varied approaches leave many questions unanswered: which anatomic target, stimulation settings, and indications seem most promising for this emerging approach.

View Article and Find Full Text PDF

Narrative review of long-standing groin pain in athletes. Retrospective analysis of over 12 000 patients.

Hernia

January 2025

Centro de Patología Herniaria Argentina, Cerviño 4449, 1425, Buenos Aires, Argentina.

Purpose: This article critically examines long-standing groin pain (LSGP) in physically active adults related to sports overload by analyzing terminology, pathophysiology, and treatment.

Method: This review is based on data from over 10,000 patients managed through a multidisciplinary algorithm. (LSGP) has been variably labeled, using terms that have led to inconsistencies in understanding its origin and management.

View Article and Find Full Text PDF

Outcomes of electrical injuries in the emergency department: epidemiology, severity predictors, and chronic sequelae.

Eur J Trauma Emerg Surg

January 2025

Emergency Department, Habib bourguiba university hospital, Faculty of Medicine, Sfax University, Majida Boulila Avenue, Sfax, Tunisia.

Introduction: Electrical injuries (EIs) represent a significant clinical challenge due to their complex pathophysiology and variable presentation, ranging from minor burns to severe internal organ damage. Despite their prevalence in both; domestic and occupational settings, there remains a rareness of systematic guidelines and comprehensive literature to aid clinicians in effectively managing these injuries. Understanding these factors is crucial for developing protocols that can mitigate the risk of delayed complications, such as cardiac arrhythmias, in patients who initially appear stable.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!