AI Article Synopsis
- The study uses 1H-NMR to analyze the metabolic profiles of genetically modified (GM) lettuce compared to conventional varieties.
- The focus is on transgenic lettuce that over-expresses the Arabidopsis KNAT1 gene, monitoring 22 water-soluble metabolites at two growth stages.
- Results show no significant differences in overall metabolite composition between GM and wild type lettuce, but the transgene does affect sugar metabolism.
Article Abstract
The 1H-NMR methodology used in the study of genetically modified (GM) foods is discussed. Transgenic lettuce (Lactuca sativa cv "Luxor") over-expressing the ArabidopsisKNAT1 gene is presented as a case study. Twenty-two water-soluble metabolites (amino acids, organic acids, sugars) present in leaves of conventional and GM lettuce were monitored by NMR and quantified at two developmental stages. The NMR spectra did not reveal any difference in metabolite composition between the GM lettuce and the wild type counterpart. Statistical analyses of metabolite variables highlighted metabolism variation as a function of leaf development as well as the transgene. A main effect of the transgene was in altering sugar metabolism.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257611 | PMC |
| http://dx.doi.org/10.3390/nu20100001 | DOI Listing |
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