Disseminated strongyloidiasis in a immunocompromised host.

Indian Pediatr

Department of Pediatrics, Kasturba Medical College, Manipal, India.

Published: December 2011

Strongyloidiasis in an immunocompromised patient has the potential to be life threatening. We describe a boy who was on steroids for acute demyelinating myelitis and receiving antibiotics for E. coli UTI and meningitis. He developed anasarca, malabsorption, malnutrition and left ventricular failure. Duodenal biopsy revealed abundant rhabditiform larvae of Strongyloides stercoralis. The diagnosis went unsuspected and proved fatal. This emphasizes the need to have a high index of suspicion and early intervention for S. stercoralis in immunosuppressed persons who present with refractory gastrointestinal symptoms.

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Article Synopsis
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  • Results showed low detection rates for strongyloidiasis; only one fecal sample tested positive through traditional cultures, while PCR and ELISA revealed 11.4% and 16.4% positivity, respectively, indicating a need for improved diagnostic methods.
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