A 70-year-old woman developed a headache for a month followed by right upper limb weakness. CT scan and MRI showed multiple ring-enhancing lesions. An intracerebral aspiration of an abscess was performed, but culture results were negative. The nucleotide sequence analysis of the 16S rRNA gene from the specimens identified Streptococcus intermedius. Given this result, S. intermedius was cultured by enrichment culture, and its sensitivities to antibiotics were determined. The patient exhibited complete remission. Thus, 16S rRNA gene analysis was highly useful not only for pathogen identification with negative culture results but also for the appropriate selection of antibiotics.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2169/internalmedicine.51.6419 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Invasive Infections in Children: Two Cases from a Pediatric Infectious Diseases Unit in Italy.
Pathogens
December 2024
Pediatric Infectious Disease Unit, Children's Hospital of Parma, 43126 Parma, Italy.
In recent years, an increasing number of reports have described invasive infections caused by bacteria from (SAGs). seems to be more related with pleuropulmonary infections and abscess of the brain and deep soft tissues, and it is more likely to cause suppurative and non-bacteremic infections compared to other members of the same genus. We present two clinical cases of invasive infections in pediatric patients: a liver abscess case and a pansinusitis case associated with bilateral otomastoiditis and parapharyngeal abscess complicated by acute mediastinitis, thrombophlebitis of the cavernous sinus, and thrombosis of the cranial tract of the ipsilateral jugular vein.
View Article and Find Full Text PDFParoxysmal sympathetic hyperactivity syndrome caused by meningoencephalitis in children: a case report and literature review.
Front Pediatr
December 2024
Department of Pediatrics, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou, Zhejiang, China.
Introduction And Importance: Paroxysmal sympathetic hyperactivity (PSH) syndrome often occurs with severe traumatic brain injury. However, it can also occur during infections, such as severe bacterial meningoencephalitis in children. is an aggressive, virulent, opportunistic pathogen.
View Article and Find Full Text PDFNovel Use of Metagenomic Next-Generation Sequencing in Diagnosing Meningitis and Ventriculitis: A Case Report and Literature Review.
Infect Drug Resist
December 2024
Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei City, Taiwan.
Background: is a commensal microflora commonly found in various mucosal sites in the respiratory, gastrointestinal, and genitourinary tracts. It causes invasive suppurative infections including liver and brain abscesses along with thoracic empyema. However, it rarely causes meningitis without abscess formation.
View Article and Find Full Text PDFSubretinal and brain abscesses caused by Streptococcus intermedius.
Lancet Infect Dis
December 2024
Ophthalmology Department, University Hospital, Saint-Etienne, France; Ophthalmology Department, Hôpital National des 15-20, Paris, France; Laboratory Biology, Engineering and Imaging for Ophthalmology, Federative Institute of Research in Sciences and Health Engineering, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France. Electronic address:
Pleural space infection microbiology as assessed using a clinical sequencing-based assay: group, and other oral normal microbiota are the most common bacteria identified in community-acquired pleural space infections.
J Clin Microbiol
December 2024
Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic., Rochester, Minnesota, USA.
Unlabelled: The definition of the microbiology of pleural space infection has been challenging due to the poor yield of conventional culture. Here, the results of a 16S ribosomal RNA gene PCR/sequencing assay performed on pleural fluid in routine clinical practice between August 2020 and January 2023 were evaluated. Amplified 16S rRNA gene DNA was submitted to Sanger sequencing and/or next-generation sequencing or results were reported as negative, depending on PCR crossing threshold value.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!