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Clinical and single-photon emission computed tomography study of pure akinesia with freezing of gait. | LitMetric
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Clinical and single-photon emission computed tomography study of pure akinesia with freezing of gait.

Imen Kacem Amina Gargouri Mouna Ben-Djebara Riadh Gouider

Neurosciences (Riyadh)

Clinical Neurophysiology and Electrodiagnosis Unit, Department of Neurology, Razi Hospital, La Manouba, Tunisia.

Published: January 2012

The clinical syndrome of pure akinesia (PA) is considered the third phenotype of progressive supranuclear palsy (PSP), and is characterized by freezing of gait and prominent speech disturbance without rigidity or tremor. It is frequently considered one of the dopamine resistant motor syndromes, and its pathophysiology remains unclear. We report a patient followed in the Department of Neurology of Razi Hospital, Tunisia, with PA with gait freezing (PAGF) with a frontal hypoperfusion on single photon emission CT and non-responsive dopa therapy. We discuss the clinical features of PAGF and efficiency of treatment options.

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