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Intracellular Membrane Contact Sites in Skeletal Muscle Cells.
Membranes (Basel)
January 2025
Department of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Intracellular organelles are common to eukaryotic cells and provide physical support for the assembly of specialized compartments. In skeletal muscle fibers, the largest intracellular organelle is the sarcoplasmic reticulum, a specialized form of the endoplasmic reticulum primarily devoted to Ca storage and release for muscle contraction. Occupying about 10% of the total cell volume, the sarcoplasmic reticulum forms multiple membrane contact sites, some of which are unique to skeletal muscle.
View Article and Find Full Text PDFPatients with multiple sclerosis and low disability display cautious rotational behavior during gait initiation.
Clin Biomech (Bristol)
January 2025
Univ. Polytechnique Hauts-de-France, LAMIH, CNRS, UMR 8201, F-59313 Valenciennes, France.
Background: Multiple sclerosis induces locomotor impairments. The objective was to characterize the effects of Multiple Sclerosis on whole-body angular momentum control during gait initiation.
Methods: Fifteen patients with Multiple Sclerosis with Expanded Disability status scale of 2.
Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures.
J Periodontal Res
January 2025
Division of Periodontology, Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts, USA.
Aim: To assess tissue perfusion changes and wound healing biomarker levels after root coverage procedures with coronally advanced flap in combination with the cross-linked xenogeneic collagen matrix (CCMX), loaded either with a placebo or recombinant human platelet-derived growth factor-BB (rhPDGF).
Methods: This study was designed as a secondary analysis from a previously published clinical trial, and it assessed the tissue perfusion changes over 6 months around multiple gingival recession defects, treated with either with CCMX alone (control) or with CCMX + rhPDGF (test). High frequency Doppler ultrasonography (HFUS) scans were obtained at sites of interest at baseline, 2 weeks, 3 months, and 6 months after surgery.
Reliability of artificial intelligence-driven markerless motion capture in gait analyses of healthy adults.
PLoS One
January 2025
Department of Kinesiology and Sport Sciences, University of Miami, Coral Gables, FL, United States of America.
The KinaTrax markerless motion capture system, used extensively in the analysis of baseball pitching and hitting, is currently being adapted for use in clinical biomechanics. In clinical and laboratory environments, repeatability is inherent to the quality of any diagnostic tool. The KinaTrax system was assessed on within- and between-session reliability for gait kinematic and spatiotemporal parameters in healthy adults.
View Article and Find Full Text PDFLaparoscopic surgery for synchronous double colorectal cancer with obstruction, plus small B cell lymphoma: a case report.
J Surg Case Rep
January 2025
Department of Gastrointestinal Surgery, Minda Hospital of Hubei Minzu University, Enshi 445099, China.
Synchronous colorectal cancer is a rare disease. It remains challenging for diagnosis and treatment. This paper reports a case of a 75-year-old Chinese male patient presenting with intestinal obstruction, alongside primary thrombocytopenia and a diagnosis of small B-cell lymphoma.
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