The outcome at two years of patients who were eligible for a study of first schizophrenic episodes was assessed in terms of occupation (n = 237) and in terms of number of days spent as an in-patient from the time of first admission (n = 252), and was related to social, behavioural, mental state and neurological measures during the initial admission. Poor outcome was in general associated with more social withdrawal, inactivity and abnormal social presentation and with more 'neurological soft signs'. Good occupational outcome in patients with a relatively short pre-treatment duration of illness was associated with the prescription of placebo medication during the follow-up period.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1192/bjp.157.2.182 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
How Do People With Schizophrenia Manage Their Daily Life? A Qualitative Study.
Int J Ment Health Nurs
February 2025
Faculty of Medicine and Health Sciences, Department of Rehabilitation Sciences, Occupational Therapy Research Group, Ghent University, Ghent, Belgium.
Due to the rising number of long-term mental health conditions, there has been a shift in therapeutic focus from curing these conditions, to living a meaningful life with them. Self-management is described as the ability to live with the emotional, life role and medical consequences of long-term conditions such as schizophrenia. However, the perspective of people with schizophrenia on self-management in current literature is missing.
View Article and Find Full Text PDFPrevalence of neurocognitive deficits in patients with first-episode schizophrenia in an African sample and its relationship with dimensions of psychopathology and psychosocial outcome.
BMC Psychiatry
December 2024
Department of Psychological Medicine, University of Nigeria, Enugu, Nigeria.
Article Synopsis
- The study investigates neurocognitive deficits (NCD) in first-episode schizophrenia (FES) patients from Africa, highlighting their prevalence and changes over 8 weeks of treatment, compared to healthy controls (HC).
- Among the FES group, 62.9% showed NCD after 8 weeks, significantly higher than just 1.2% in the HC group, with improvements in cognitive function noted at each follow-up.
- The results indicate that better cognitive performance in FES correlates with lower psychopathology scores, suggesting a potential link between cognitive function and overall mental health outcomes in schizophrenia.
Assessing the Trajectory of Schizophrenia Effectively in Order to Treat Effectively.
Psychiatr Danub
September 2024
One Time Clare College Research Associate, Cambridge, UK,
Article Synopsis
- Schizophrenia is a complex disorder with varied symptom trajectories that significantly affect patient outcomes; studying these trajectories can help assess treatment options and results.
- The Positive and Negative Syndrome Scale (PANSS) can be used repeatedly in clinical settings to measure symptom changes over time, highlighting the importance of longitudinal studies in understanding these trajectories.
- Research shows variability in positive symptom trajectories, with some patients experiencing remission while others have persistent symptoms; negative symptoms generally show limited improvement and are linked to poorer social and cognitive functioning, all of which affect overall treatment effectiveness.
Peak width of skeletonized mean diffusivity as a neuroimaging biomarker in first-episode schizophrenia.
Front Neurosci
September 2024
Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background And Objective: Peak width of skeletonized mean diffusivity (PSMD), a fully automated diffusion tensor imaging (DTI) biomarker of white matter (WM) microstructure damage, has been shown to be associated with cognition in various WM pathologies. However, its application in schizophrenic disease remains unexplored. This study aims to investigate PSMD along with other DTI markers in first-episode schizophrenia patients compared to healthy controls (HCs), and explore the correlations between these metrics and clinical characteristics.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!