[Iridoid glycosides from buds of Jasminum officinale L. var. grandiflorum].

Yao Xue Xue Bao

Hebei Key Laboratory of Research and Development for Traditional Chinese Medicine, Institute of Chinese Materia Medica, Chengde Medical College, Chengde 067000, China.

Published: October 2011

The study on the buds of Jasminum officinale L. var. grandiflorum was carried out to look for anti-HBV constituents. The isolation and purification were performed by HPLC and chromatography on silica gel, polyamide and Sephadex LH-20 column. The structures were elucidated on the basis of physicochemical properties and spectral analysis. Six iridoid glycosides were identified as jasgranoside B (1), 6-O-methy-catalpol (2), deacetyl asperulosidic acid (3), aucubin (4), 8-dehydroxy shanzhiside (5), and loganin (6). Jasgranoside B (1) is a new compound. Compounds 2-6 were isolated from Jasminum officinale L. var. grandiflorum for the first time.

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