AI Article Synopsis
- Dengue is a major mosquito-borne disease caused by a single-stranded RNA virus from the Flaviviridae family, with four serotypes (DEN 1-4) affecting millions globally.
- Around 100 million cases of dengue fever and 500,000 cases of dengue hemorrhagic fever (DHF) occur each year, with 2.5 billion people at risk and the disease being endemic in 112 countries.
- Timely diagnosis and treatment are crucial to reduce serious complications and fatalities, as evidenced by a case involving a patient with dengue fever who tragically suffered a fatal intracranial hemorrhage.
Article Abstract
Dengue viral infections are one of the most important mosquito borne diseases in the world. The dengue virus is a single stranded RNA virus belonging to the Flaviviridae family. There are four serotypes (DEN 1-4) classified according to biological and immunological criteria. Patients may be asymptomatic or their condition may give rise to undifferentiated fever, dengue fever, dengue haemorrhagic fever (DHF), or dengue shock syndrome. Annually, 100 million cases of dengue fever and half a million cases of DHF occur worldwide and 2.5 billion people are at risk. At present, dengue is endemic in 112 countries. Early recognition and prompt initiation of appropriate treatment are vital if disease related morbidity and mortality are to be limited. We present an interesting case of dengue fever with headache, skin rash and abnormal behaviour who had a massive intracranial haemorrhage with fatal outcome.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029086 | PMC |
| http://dx.doi.org/10.1136/bcr.06.2009.1949 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A low pre-existing anti-NS1 humoral immunity to DENV is associated with microcephaly development after gestational ZIKV exposure.
PLoS Negl Trop Dis
January 2025
División de Inmunología, Programa de Medicina, Facultad de Ciencias de la Salud, Universidad Surcolombiana, Neiva, Huila, Colombia.
Background: Gestational Zika virus (ZIKV) infection is associated with the development of congenital Zika syndrome (CZS), which includes microcephaly and fetal demise. The magnitude and quality of orthoflavivirus-specific humoral immunity have been previously linked to the development of CZS. However, the role of ZIKV NS1-specific humoral immunity in mothers and children with prenatal ZIKV exposure and CZS remains undefined.
View Article and Find Full Text PDFFirst detection of the S989P+V1016G+D1763Y haplotype and expansion of voltage-gated sodium channel mutations in Aedes aegypti in Taiwan in 2016-2023.
PLoS Negl Trop Dis
January 2025
Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan.
Background: Aedes aegypti transmits various arthropod-borne diseases such as dengue, posing a significant burden to public health in tropical and subtropical regions. Pyrethroid-based control strategies are effective in managing this vector; however, the development of insecticide resistance has hindered these efforts. Hence, long-term monitoring of insecticide resistance in mosquito populations is crucial for effective vector and disease control.
View Article and Find Full Text PDFElevated developmental temperatures below the lethal limit reduce Aedes aegypti fertility.
J Exp Biol
January 2025
School of BioSciences, Bio21 Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.
Aedes aegypti mosquitoes are the principal vectors of dengue and continue to pose a threat to human health, with ongoing urbanization, climate change, and trade all impacting the distribution and abundance of this species. Hot periods are becoming increasingly common and their impacts on insect mortality have been well established, but they may have even greater impacts on insect fertility. In this study, we investigated the impacts of high temperatures on Ae.
View Article and Find Full Text PDFDengue Fever in an Adult Presenting as Immune Thrombocytopenic Purpura (ITP): A Case Report.
Cureus
December 2024
General Medicine, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, IND.
Immune thrombocytopenic purpura (ITP) is an autoimmune self-limiting disorder characterized by a decreased platelet count. Usually, it affects children after viral infections. Adults often develop chronic ITP, but they can also develop ITP following viral infections, which is uncommon.
View Article and Find Full Text PDFAssessing the Diagnostic Value of Mean Monocyte Volume and Hematological Parameters in Predicting Dengue Fever: A Cross-Sectional Analysis.
Cureus
December 2024
Department of Hematology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.
Background And Aim: Distinguishing dengue fever (DF) from other viral infections solely based on common presentations poses a challenge. Therefore, there is a pressing need for additional diagnostic parameters that are reliable, swift, and cost-effective. This study aims to provide novel insights into the diagnostic value of hematological parameters, particularly mean monocyte volume (MMV), in predicting DF in Kelantan, Malaysia.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!