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Keratin Positive Giant Cell Rich Tumor of the Pelvic Bone with a Fusion: A Case Report.
Int J Surg Pathol
January 2025
Department of orthopedic oncology, UZ Leuven, Leuven, Belgium.
Keratin positive giant cell rich tumor is a rare mesenchymal tumor first described in 2025. It can occur in both soft tissue and bone and predominantly affects young women. The tumor's biological behavior remains uncertain despite its low-grade classification.
View Article and Find Full Text PDFA Neglected Case of a Benign Phyllodes Tumor Presenting as a 10.5 kg Breast Mass.
Cureus
December 2024
General Surgery, Rajendra Institute of Medical Sciences, Ranchi, IND.
Phyllodes tumor is a type of fibroepithelial neoplasm involving the breast. This tumor is rarely reported in adolescents and the elderly and has a peak incidence in middle-aged women. Histologically, phyllodes tumors are classified as benign, borderline, or malignant.
View Article and Find Full Text PDFRole of Morphology in the Diagnosis of an Unsuspected Case of Chediak-Higashi Syndrome: A Case Report.
Cureus
December 2024
Department of Pathology, Ranga Raya Medical College, Kakinada, IND.
Chediak-Higashi syndrome (CHS) is a rare multisystem genetic disorder of childhood, caused by a defect in vesicular trafficking, which is an essential process for intracellular transport. This defect results in the formation of giant cytoplasmic granules in various cell types, including white blood cells, melanosomes, and Schwann cells. The presence of giant lysosomal granules in neutrophils and their precursors is a distinct and diagnostic feature of CHS, differentiating it from other childhood immunodeficiency disorders, such as Griscelli syndrome and Hermansky-Pudlak syndrome, which share common characteristics like albinism and increased susceptibility to fatal hemophagocytic lymphohistiocytosis.
View Article and Find Full Text PDFSystemic siliconomas following breast implant rupture.
BMJ Case Rep
January 2025
General Surgery, Universidade de Lisboa Faculdade de Medicina, Lisboa, Portugal.
We report a case of a woman in her late 40s with a history of breast implant surgery following breast cancer treatment. She presented with asymmetrical breast enlargement, palpable contralateral axillary lymph nodes and cutaneous nodules on both forearms. In addition, imaging evaluation revealed intracapsular implant rupture, ipsilateral internal mammary enlarged lymph nodes and multiple mediastinal lymphadenopathies.
View Article and Find Full Text PDFRecurrence of a Giant-Cell Tumor of the Wrist with Malignant Transformation and Pulmonary Metastases Treated with a Custom-Made Prosthesis.
Hand Surg Rehabil
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Università Cattolica del Sacro Cuore, Rome, Italy; UOC Ortopedia e Traumatologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
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