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Dysregulated Clot Mechanics and Kinetics Impacted by Injury Severity, Predict Mortality After Trauma.
Shock
January 2025
Department of Biomedical Engineering, Rutgers University, Piscataway, NJ 599 Taylor Road, Room 209, Piscataway, NJ, USA 08854.
Introduction: Coagulopathy following traumatic injury impairs stable blood clot formation and exacerbates mortality from hemorrhage. Understanding how these alterations impact blood clot stability is critical to improving resuscitation. Furthermore, the incorporation of machine learning algorithms to assess clinical markers, coagulation assays and biochemical assays allows us to define the contributions of these factors to mortality.
View Article and Find Full Text PDFCellulose and Cellulose Nanomaterials: Recent Research and Applications in Medical Field.
Comb Chem High Throughput Screen
January 2025
Pharmaceutics Division, Department of Pharmaceutical Sciences, University of Kashmir, Hazratbal, Srinagar-190006, Jammu and Kashmir, India.
Cellulose, the most prevalent biopolymer in the world, is comprehensively reviewed. Cellulose occurs in fibrillar patterns with alternating crystalline and amorphous regions. The non-toxic and -friendly nature of cellulose has made it beneficial in many fields, such as pharmaceuticals, biomedical, nanotechnology, etc.
View Article and Find Full Text PDFA lubcan cross-linked polyethylene glycol dimethyl ether hydrogel for hyaluronic acid replacement as soft tissue engineering fillers.
Int J Biol Macromol
January 2025
Center for Molecular Metabolism, Nanjing University of Science & Technology, Nanjing 210094, China; Key Laboratory of Metabolic Engineering and Biosynthesis Technology, Ministry of Industry and Information Technology, 210094, China. Electronic address:
The structure of soft tissues is often destroyed by injury and aging. Injectable fillers eliminate the need for surgery and enhance repair. Hyaluronic acid-based hydrogels are commonly employed for their effectiveness and biocompatibility.
View Article and Find Full Text PDFThe Effect of a Secondary Stressor on the Morphology and Membrane Structure of an Already Challenged Maternal and Foetal Red Blood Cell Population.
Int J Mol Sci
January 2025
Department of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6701 Szeged, Hungary.
The red blood cell (RBC) membrane is unique and crucial for maintaining structural-functional relationships. Maternal smoking induces significant changes in the morphological, rheological, and functional parameters of both maternal and foetal RBCs, mainly due to the continuous generation of the free radicals. The major aim of this study was to follow the consequences of a secondary stressor, like fungal infection, on the already compromised RBC populations.
View Article and Find Full Text PDFImpacts of variable magnetic field on ternary Casson nanofluid flow through ciliated arterial walls incorporating interfacial nanolayer.
Electromagn Biol Med
January 2025
Department of Applied Mathematics, University of Calcutta, Kolkata, India.
The current investigation explores tri-hybrid mediated blood flow through a ciliary annular model, designed to emulate an endoscopic environment. The human circulatory system, driven by the metachronal ciliary waves, is examined in this study to understand how ternary nanoparticles influence wave-like flow dynamics in the presence of interfacial nanolayers. We also analyze the effect of an induced magnetic field on Ag-Cu-/blood flow within the annulus, focusing on thermal radiation, heat sources, buoyancy forces and ciliary motion.
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