An analysis of results of treatment of 323 patients with aneurysm of the abdominal and thoraco-abdominal parts of the aorta was made for the period from 1995 through 2010. The patients' age was within the limits from 45 to 88 years and was 67.2 +/- 6.5 at an average. In 65 (24.5%) patients the diagnosis of progressing type aneurysmatic disease of the aorta and other main arteries was made. At the department of surgery of vessels of the Yaroslavl regional clinical hospital (YRCH) planned operations were performed on 102 (31.6%) patients, by emergency indications--on 69 (21.3%), with the clinical picture of rupture on 25 (7.8%) patients. In addition, 58 (17.9%) patients were operated by emergency indications under conditions of the Central regional hospital (CRH). Dynamic follow-up was fulfilled in 69 (21.4%) cases. Results of the operative treatment in greater degree depended on the emergency of surgery and severity of the concomitant pathology. Common lethality after planned operations was 5.9%, emergent--20.3%, aneurysm rupture under conditions of CRH--91.4% of cases. Lethality in YRCH in emergent operations was considerably lower--52% of cases. Use of screening examinations in groups of risk beginning from 50 years of age and the population older than 60, active surgical strategy in small aneurysms, introduction of minimally traumatic operative approaches allow improvement of results of the treatment.
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J Coll Physicians Surg Pak
January 2025
Department of General and Laparoscopic Surgery, Sheikh Khalifa Bin Zayed Al-Nahyan Hospital Muzaffarabad, Azad Jammu and Kashmir, Pakistan.
Objective: To determine the importance of the Glasgow Coma scale (GCS), ASA physical status classification system, and P-POSSUM score in predicting mortality among patients undergoing emergency laparotomies.
Study Design: An analytical study. Place and Duration of the Study: Department of General Surgery, Sheikh Khalifa Bin Zayed Al-Nahyan Hospital Muzaffarabad, Pakistan, from October 2020 to January 2022.
Eur J Vasc Endovasc Surg
January 2025
Department of Vascular Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Int J Surg Case Rep
January 2025
Karnali Academy of Health Science, Jumla, Nepal.
Introduction And Importance: Splenic artery aneurysm is extremely rare but potentially life threatening disease which poses great challenge in diagnosing due to non-specific nature of clinical presentation. Rarely, it presents with upper gastrointestinal bleeding i.e.
View Article and Find Full Text PDFJ Cell Mol Med
January 2025
State Key Laboratory of Frigid Zone Cardiovascular Diseases, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China.
Abdominal aortic aneurysm (AAA) is the most prevalent dilated arterial aneurysm that poses a significant threat to older adults, but the molecular mechanisms linking senescence to AAA progression remain poorly understood. This study aims to identify cellular senescence-related genes (SRGs) implicated in AAA development and assess their potential as therapeutic targets. Four hundred and twenty-nine differentially expressed genes (DEGs) were identified from the GSE57691 training set, and 867 SRGs were obtained.
View Article and Find Full Text PDFCardiovasc Intervent Radiol
January 2025
Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
Purpose: To investigate the influence of antithrombotic therapy on occurrence of thrombotic and bleeding complications after endovascular aneurysm repair (EVAR).
Methods: In this retrospective single-center cohort study, patients who underwent elective endovascular aneurysm repair for abdominal aortic aneurysm were categorized into three antithrombotic groups: single antiplatelet therapy (SAPT), anticoagulants, or dual antiplatelet therapy (DAPT). Outcome measures were the incidence of major adverse cardiovascular events (MACE), prosthetic limb occlusions, and bleeding complications during follow-up.
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