Purpose: To verify the aesthetic impact of mild and moderate dental fluorosis on young adult students from the UFMG using pictures with different fluorosis levels simulated in a computer program.
Materials And Methods: The sample consisted of 396 university students, randomly selected from various courses (except dentistry). These participants were shown three mouth pictures with different rates of dental fluorosis (TFO, TF2 and TF4) according to the Thylstrup-Fejerskov Index (TF). The volunteers gave an individual assessment of the pictures and graded them (from 1 to 10) based on their aesthetics. In addition, they answered if they would feel uncomfortable smiling and if they would seek dental treatment in each case. The results were submitted to a chi-square test (P < 0.05).
Results: The students preferred the TF4 picture to the TF2. The picture which presented no fluorosis was more often preferred than the pictures which presented some form of change due to fluorosis. Higher scores were recorded by men for the TF2 picture than by women (P < 0.05). As for the TF0 and TF4 pictures, the scores were similar among males and females. Furthermore, women reported more discomfort in smiling (P = 0.001) and a greater desire to seek out dental treatment than did men. Only 27.5% of all students stated that they knew what dental fluorosis was.
Conclusion: Mild and moderate dental fluorosis had a negative aesthetic effect on the studied population, leading to a strong desire to seek dental treatment to change the appearance of affected teeth.
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Chem Phys Lipids
January 2025
College & Hospital of Stomatology, Anhui Medical University, Key Lab. of Oral Diseases Research of Anhui Province, No.81, Meishan Road, Shushan District, Hefei 230032, China. Electronic address:
Dental fluorosis, as a common chronic fluoride toxicity oral disease, is mainly caused by long-term excessive intake of fluoride, which seriously affects the aesthetics and function of patients' teeth. In recent years, with the rapid development of metabolomics technology, lipidomics, as an important means to study the changes in lipid metabolism in organisms, has shown great potential in revealing the mechanisms of disease development. As a major component of cell membranes and a signaling molecule, metabolic disorders of lipids are closely related to a variety of diseases, but the specific mechanism of action in dental fluorosis is still unclear.
View Article and Find Full Text PDFJAMA Pediatr
January 2025
Division of Translational Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.
Importance: Previous meta-analyses suggest that fluoride exposure is adversely associated with children's IQ scores. An individual's total fluoride exposure comes primarily from fluoride in drinking water, food, and beverages.
Objective: To perform a systematic review and meta-analysis of epidemiological studies investigating children's IQ scores and prenatal or postnatal fluoride exposure.
Heliyon
December 2024
Department of Computer Science and Engineering, Anand Engineering College, Agra, India.
Groundwater contamination with fluoride is a considerable public health concern that affects millions of people worldwide. The rapid growth of urbanization has led to increase in groundwater contamination. The health risk assessment focuses on both acute and chronic health consequences as it investigates the extent and effects of fluoride exposure through contaminated groundwater.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province & Ministry of Health (23618504), Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, Heilongjiang Province 150081, China. Electronic address:
Fluorine is a strong oxidizing element and excessive intake can have harmful effects, particularly on the body's calcified tissues. Recent studies have demonstrated a link between miRNA and fluorosis. This study aimed to evaluate the time-dose-effect relationship of miR-200c-3p in plasma, urine and cartilage of rats with drinking water fluorosis, and to explore its potential as a biomarker.
View Article and Find Full Text PDFSci Rep
December 2024
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, 150081, Heilongjiang, China.
High fluoride concentrations in groundwater represent a substantial global public health concern. In China, over 70 million individuals suffer from drinking water fluorosis. This study reports national surveillance data in 2014 and 2018, dividing affected areas into six regions.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!