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Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope. | LitMetric
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Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope.

Aélig Robin Valentin Köhler Alison Jones Afruja Ali Paul P Kelly Elaine O'Reilly Nicholas J Turner Sabine L Flitsch

Beilstein J Org Chem

School of Chemistry & Manchester Interdisciplinary Biocentre (MIB), University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom.

Published: August 2012

A high-throughput screening protocol for evaluating chimeric, self-sufficient P450 biocatalysts and their mutants against a panel of substrates was developed, leading to the identification of a number of novel biooxidation activities.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252848PMC
http://dx.doi.org/10.3762/bjoc.7.173DOI Listing

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