The complex study of the physical development of boys and girls aged 11-18 years of native and newly come population of Khanty-Mansiysk-Ugra Autonomous Region was performed. It was found that the native population had higher mass of fat component in all the age groups as compared to that of the newly come population. The data obtained reflect the regional peculiarities of the growth processes of the children of native and newly come population. These data help to reveal the mechanisms providing adaptive character of development at the pubertal stage the ontogenesis.
Download full-text PDF |
Source |
---|
Ann Intern Med
January 2025
Durham VA Health Care System, Durham; and Division of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina (K.M.G.).
Background: Tissue-based genomic classifiers (GCs) have been developed to improve prostate cancer (PCa) risk assessment and treatment recommendations.
Purpose: To summarize the impact of the Decipher, Oncotype DX Genomic Prostate Score (GPS), and Prolaris GCs on risk stratification and patient-clinician decisions on treatment choice among patients with localized PCa considering first-line treatment.
Data Sources: MEDLINE, EMBASE, and Web of Science published from January 2010 to August 2024.
Ther Adv Respir Dis
January 2025
Department of Chest Medicine, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Road, Beitou District, Taipei City 11217, Taiwan.
Background: REMIT is the first real-world study of mepolizumab effectiveness in patients with severe asthma (SA) in Taiwan.
Objectives: The primary objective evaluated changes in clinically significant exacerbations (CSEs; defined as use of oral corticosteroids (OCS) or emergency department (ED) visits and/or hospitalizations) in the 12 months pre- and post-mepolizumab treatment. Secondary objectives assessed changes in the number of CSEs requiring ED visits/hospitalizations and daily maintenance OCS (mOCS) dosage 12 months pre- and post-mepolizumab treatment.
Diabetes Obes Metab
January 2025
AstraZeneca R&D Pharmaceuticals, Gaithersburg, Maryland, USA.
Aims: Recommendations on the use of newer type 2 diabetes (T2D) treatments (e.g., SGLT2 inhibitors and GLP-1 receptor agonists [RA]) in contemporary clinical guidelines necessitate a change in how T2D models approach therapy selection and escalation.
View Article and Find Full Text PDFEur J Oncol Nurs
January 2025
West China School of Nursing/West China Hospital, Sichuan University, 37 Guoxue Xiang Street, Chengdu, 610041, Sichuan Province, China. Electronic address:
Purpose: The research aimed to investigate the prevalence of PTSD in newly diagnosed Chinese women with breast cancer and to distinguish a munber of sociodemographic, disease-related and psychosocial factors connected with the severity of PTSD symptom.
Methods: This cross-sectional study recruited 674 newly diagnosed Chinese women with breast cancer at three tertiary level a general hospitals in Chengdu, China between August 2022 and May 2023. And questionnaires about general information, locus of control, social support, coping styles, emotional regulation and PTSD were filled out.
J Gastroenterol Hepatol
January 2025
Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Diseases Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, China.
Background: Similar worsening epidemics globally have been showed in newly coined metabolic dysfunction-associated steatotic liver disease (MASLD) and inflammatory bowel disease (IBD). We aimed to investigate the prospective association of MASLD, MASLD types, and cardiometabolic risk factors (CMRFs) with long-term risk of incident IBD in a large-scale population cohort.
Methods: Participants free of IBD at enrollment from UK Biobank were included.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!