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Biomarkers and Social Determinants in atherosclerotic Arterial Diseases: A Scoping Review.
Ann Vasc Surg
January 2025
Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy; Interuniversity Center of Phlebolymphology (CIFL), "Magna Graecia" University, 88100 Catanzaro, Italy. Electronic address:
Background: Arterial diseases like coronary artery disease, carotid stenosis, peripheral artery disease, and abdominal aortic aneurysm have high morbidity and mortality, making them key research areas. Their multifactorial nature complicates patient treatment and prevention. Biomarkers offer insights into the biochemical and molecular processes, while social factors also significantly impact patients' health and quality of life.
View Article and Find Full Text PDFDiscontinuous named entities in clinical Text: A systematic literature review.
J Biomed Inform
January 2025
University of Manchester, United Kingdom.
Objective: Extracting named entities from clinical free-text presents unique challenges, particularly when dealing with discontinuous entities-mentions that are separated by unrelated words. Traditional NER methods often struggle to accurately identify these entities, prompting the development of specialised computational solutions. This paper systematically reviews and presents the methodologies developed for Discontinuous Named Entity Recognition in clinical texts, highlighting their effectiveness and the challenges they face.
View Article and Find Full Text PDFAn inventory analysis of waste tyre generation and management in South Africa.
Waste Manag
January 2025
Green Engineering Research Group, Department of Chemical Engineering, Faculty of Engineering and The Built Environment, Durban University of Technology, Durban 4001, South Africa.
Global waste generation, particularly waste tyres, is a significant issue, with South Africa contributing significantly to this problem. In 2021, 1.5 billion waste tyres were generated, with an expected 4.
View Article and Find Full Text PDFImproving Replication in Endometrial Omics: Understanding the Influence of the Menstrual Cycle.
Int J Mol Sci
January 2025
Department of Obstetrics and Gynaecology, University of Melbourne, and Gynaecology Research Centre, Royal Women's Hospital, Parkville, VIC 3052, Australia.
The dynamic nature of human endometrial tissue presents unique challenges in analysis. Despite extensive research into endometrial disorders such as endometriosis and infertility, recent systematic reviews have highlighted concerning issues with the reproducibility of omics studies attempting to identify biomarkers. This review examines factors contributing to poor reproducibility in endometrial omics research.
View Article and Find Full Text PDFQuantification of Myocardial Biomarkers in Sudden Cardiac Deaths Using a Rapid Immunofluorescence Method for Simultaneous Biomarker Analysis.
Biomedicines
January 2025
Institute of Legal Medicine, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Background/objectives: Differential diagnosis of sudden cardiac death (SCD) remains challenging, particularly in cases lacking evident structural abnormalities. Cardiac markers have been proposed as useful tools for this differentiation in forensic contexts. However, key issues include the influence of postmortem interval (PMI) on marker stability and the limitations of traditional approaches that focus on pericardial fluid, which requires invasive sampling compared to peripheral blood.
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