Aim: The study of the Mondor's syndrome as a possible complication of gigantomastia.
Material And Method: A 49 year old woman, with gigantomastia, came to our observation for the presence of a large superficial vein of the left breast affected by thrombophlebitis, compatible with Mondor's syndrome.
Results: A "Thorek" breast reduction was performed; the patient was discharged on the second postoperative day and the follow up was smooth and fee from any complications.
Discussion: In the case we observed, gigantomastia had a clear role in the pathogenesis of the Mondor's disease; in fact, the excessive weight of the breasts caused stretching of the mammary dorsal vein evolving in phlebitis. In literature, among the causes related to Mondor's disease the pendulous breast is described, probably with the same dynamic we have seen in this patient, but has never reported, so obviously, the correlation between the two events. It's considered as good practice in the pre-operative evaluation, to make differential diagnosis with any cancer, that, in a certain percentage, is associated with Mondor's syndrome, and once established the causes of the pathology, it is imperative to eliminate them to prevent any relapses.
Conclusion: Among the various causes recognized as predisposing to Mondor's syndrome, there has never been described gigantomastia so far. The observation and treatment of a patient in whom the gigantomastia certainly led to the onset of Mondor's disease, has led us to consider this as one of the possible complications of gigantomastia, providing an additional cue to the treatment of this condition even at an early stage.
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Background: Hypereosinophilic syndromes (HES) are a heterogenous group of eosinophilic disorders. To date, only retrospective studies of limited sample-size and/or follow-up duration are available.
Methods: The COHESion study is a national prospective multicenter multidisciplinary cohort recruiting both adults or children with the spectrum of eosinophilic disorders (including reactive HE/HES [HE/HES-R], idiopathic HES [HES-I], lymphocytic HES [HES-L], neoplastic HE/HES [HE/HES-N], HE of unknown significance [HE-US], as well as IgG4-related disease [IgG4RD] or ANCA-negative eosinophilic granulomatosis with polyangiitis [EGPA] overlaps).
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AP-HP, Hôpitaux Universitaires Henri-Mondor, Service de Médecine Intensive Réanimation, 94010, Créteil, France.
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View Article and Find Full Text PDFEClinicalMedicine
January 2025
Department of Dermatology, Saint-Louis Hospital, AP-HP, Paris, France.
[This corrects the article DOI: 10.1016/j.eclinm.
View Article and Find Full Text PDFAnaesth Crit Care Pain Med
December 2024
Sorbonne University, GRC 29, Assistance Publique-Hôpitaux de Paris, DMU DREAM, Department of Anesthesiology and critical care, Pitié-Salpêtrière Hospital, Paris, France. Electronic address:
Background: Indications for Veno-venous (VV) or veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) after trauma rely on poor evidence. The main aims were to describe the population of trauma patients requiring either VV or VA ECMO and report their clinical management and outcomes.
Methods: An observational multicentre retrospective study was conducted in 17 Level 1 trauma centres in France between January 2010 and December 2021.
Kidney Int Rep
December 2024
Centre de Référence Maladies Rares Syndrome Néphrotique Idiopathique, Centre Hospitier Universitaire de Nice, Nice, France.
Introduction: Membranous nephropathy can lead to end-stage kidney disease, for which kidney transplantation is the preferred therapy. However, the disease often relapses, which can impact allograft survival.
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