The uptake and depuration of a range of pharmaceuticals in the freshwater shrimp (Gammarus pulex) and the water boatman (Notonecta glauca) was studied. For one compound, studies were also done using the freshwater snail Planobarius corneus. In G. pulex, bioconcentration factors (BCFs) ranged from 4.6 to 185,900 and increased in the order moclobemide < 5-fluoruracil < carbamazepine < diazepam < carvedilol < fluoxetine. In N. glauca BCFs ranged from 0.1 to 1.6 and increased in the order 5-fluorouracil < carbamazepine < moclobemide < diazepam < fluoxetine < carvedilol. For P. corneus, the BCF for carvedilol was 57.3. The differences in degree of uptake across the three organisms may be due to differences in mode of respiration, behaviour and the pH of the test system. BCFs of the pharmaceuticals for each organism were correlated to the pH-corrected liposome-water partition coefficient of the pharmaceuticals.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.envpol.2011.11.029 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Arsenic accumulation and reproductive toxicity in freshwater snail (Pomacea canaliculata).
Ecotoxicol Environ Saf
January 2025
Guangdong Laboratory for Lingnan Modern Agriculture, Guangdong Provincial Key Laboratory of Agricultural & Rural Pollution Abatement and Environmental Safety, College of Natural Resources and Environment, South China Agricultural University, Guangzhou 510642, China. Electronic address:
This study aimed to investigate the tissue-specific accumulation patterns of arsenic (As) and the potential toxicological effects of As on the oviposition of a globally distributed aquatic invertebrate, the apple snail (Pomacea canaliculata). An eight-compartment physiologically based pharmacokinetic (PBPK) model was utilized to simulate the distribution and depuration kinetics of arsenite and arsenate in the snails. Modeling and biotransformation suggested that intestine-stomach was the main uptake site for As and plays an important role in maintaining the balance of As species.
View Article and Find Full Text PDFFrom microalgae to gastropods: Understanding the kinetics and toxicity of silver nanoparticles in freshwater aquatic environment.
Environ Pollut
January 2025
Department F.-A. Forel for Environmental and Aquatic Sciences, Section Earth and Environmental Sciences, Faculty of Sciences, University of Geneva, 66 Blvd Carl-Vogt, CH, 1211, Geneva, Switzerland. Electronic address:
Silver nanoparticles (AgNPs) are increasingly used in various consumer products and industrial applications, raising concerns about their environmental impact on aquatic ecosystems. This study investigated the physicochemical stability, trophic transfer, and toxic effects of citrate-coated AgNPs in a freshwater food chain including the diatom Cyclotella meneghiniana and the gastropod Lymnaea stagnalis. AgNPs remained stable in the exposure medium, with a minimal dissolution (<0.
View Article and Find Full Text PDFMetal uptake in wetland plants from oil sands process-affected waters: a case study.
Environ Technol
December 2024
Worley Consulting, Fort Collins, CO, USA.
Treatment wetlands have emerged as a potential remediation option for oil-sands process affected waters (OSPW) which contains a suite of organic and inorganic constituents of potential concern. The aim of this study was to evaluate the fate of metals in a treatment wetland exposed to OSPW. Data was collected over three operational seasons testing freshwater and OSPW inputs at the Kearl Treatment Wetland in northern Alberta.
View Article and Find Full Text PDFExploring the depuration of metals in the green shore crab (Carcinus maenas): Studies with radiolabelled calcium, zinc, and nickel.
Sci Total Environ
December 2024
Bamfield Marine Science Centre, Bamfield, British Columbia V0R 1B0, Canada; University of British Columbia, Department of Zoology, Vancouver, BC V6T 1Z4, Canada; McMaster University, Dept. of Biology, Hamilton, Ontario L8S 4K1, Canada.
The depuration of newly accumulated metal from the crab Carcinus maenas (inter-moult stage) was studied, with a particular focus on the carapace, in light of recent findings that it is a major site for direct uptake and incorporation of Ca, Zn, and Ni from the external sea water. Crabs were exposed for 24 h to calcium ([Ca] = 389 mg L or 9.7 mmol L), zinc ([Zn] = 82 μg L or 1.
View Article and Find Full Text PDFDifferences in Toxicokinetics and Maternal Transfer between Lipophilic and Proteinophilic Halogenated Organic Pollutants in Laying Hens.
Environ Health (Wash)
October 2024
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, P. R. China.
Article Synopsis
- - The study examined how lipophilic (like PCBs and PBDEs) and proteinophilic (like PFCAs) halogenated organic pollutants (HOPs) behave in egg-laying hens, focusing on their toxicokinetics and the transfer to eggs.
- - Results showed that lipophilic HOPs had slower depuration rates and showed a specific correlation between their levels and fat content, whereas PFCAs showed a different relationship with protein content.
- - PFCAs were found to have a higher maternal transfer potential (over 80%) into eggs compared to lipophilic HOPs (around 30% for some compounds), indicating significant differences in how these pollutants accumulate and affect hen
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!