AI Article Synopsis
- The study utilized both on-line (HPLC-NMR) and off-line (HPLC, NMR, MS) techniques to analyze the compounds in Lasiopetalum macrophyllum.
- The research confirmed the presence of trans-tiliroside and identified other related compounds, including a new flavonoid glycoside, 4'-methoxy-cis-tiliroside.
- This represents the first discovery of flavonoid glycosides in this plant genus and suggests corrections to the structural assignments of previously identified flavonoids.
Article Abstract
On-line (HPLC-NMR) and off-line (HPLC, NMR and MS) methodologies were used to profile the constituents present in the crude extract of Lasiopetalum macrophyllum. On-flow and stop-flow HPLC-NMR supported the presence of trans-tiliroside and permitted partial identification of cis-tiliroside and 4'-methoxy-trans-tiliroside. Off-line isolation led to the unequivocal identification of four flavanoid glycosides including a new structural derivative, 4'-methoxy-cis-tiliroside. This is the first report of flavonoid glycosides occurring in this plant genus. In addition, a number of structure revisions have been proposed for previously reported flavonoid glycosides that were incorrectly assigned.
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Article Synopsis
- The study utilized both on-line (HPLC-NMR) and off-line (HPLC, NMR, MS) techniques to analyze the compounds in Lasiopetalum macrophyllum.
- The research confirmed the presence of trans-tiliroside and identified other related compounds, including a new flavonoid glycoside, 4'-methoxy-cis-tiliroside.
- This represents the first discovery of flavonoid glycosides in this plant genus and suggests corrections to the structural assignments of previously identified flavonoids.
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