From the methylene chloride extract of the stem bark of Beilschmiedia obscura, a new cyclostachine derivative, obscurine (1), has been isolated, together with six known compounds. The structure of compound 1 was established by spectroscopic methods, including 1- and 2-dimensional NMR techniques.
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Metabol Open
March 2022
Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
Introduction: (Lauraceae) is a pantropical genus of about 287 species, distributed in tropical Asia and Africa used in traditional medicines to cure many diseases. This study aimed to explore biological properties of () on the prevention and management of metabolic syndrome (MetS) features induced by High Fat/High Sucrose (HF/HS) diet in rats as therapeutic option.
Methods: MetS was induced after administration of HF/HS diet followed by administration of powder at 5% or 10% for 21 days, while the control group received a chow diet and distilled water and the positive control group received the HF/HS diet and distilled water.
Heliyon
July 2020
Department of Food Science and Nutrition, The University of Ngaoundere, P.O Box 455 Ngaoundere, Cameroon.
Encapsulation in alginate beads has always been limited by the leakage due to the too wide distribution of pore sizes. Mixing alginate with other polymers have sometimes reduced the problem. Hydrocolloids from seven tropical vegetal species (barks of and seeds of and , and leaves of and ) were screened for synergistic interactions with alginate in dilute aqueous solution.
View Article and Find Full Text PDFMolecules
June 2020
Department of Chemistry, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa.
The MeOH/CHCl (1:1) extracts of the roots and leaves of and showed potent antitrypanosomal activity during preliminary screening on . Phytochemical investigation of these extracts led to the isolation of a mixture of two new endiandric acid derivatives beilschmiedol B () and beilschmiedol C (), and one new phenylalkene obscurene A () together with twelve known compounds (-). In addition, four new derivatives (-) were synthesized from compound .
View Article and Find Full Text PDFBMC Complement Altern Med
July 2014
Department of Biochemistry, Faculty of science, University of Dschang, P,O, Box 67, Dschang, Cameroon.
Nat Prod Commun
November 2011
Department of Chemistry, Higher Teachers' Training College, University of Yaoundé 1, P.O. Box 47, Yaoundé, Cameroon.
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