AI Article Synopsis

  • Scurvy is a serious but treatable disease caused by a lack of vitamin C, primarily affecting low-income individuals and smokers.
  • The deficiency leads to poor collagen formation, resulting in brittle bones, microfractures, and slow healing.
  • A case study is presented about a 5-year-old boy initially suspected of having leukemia, but a bone marrow biopsy revealed a condition related to scurvy instead.

Article Abstract

Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.

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Source
http://dx.doi.org/10.1007/s00256-011-1350-9DOI Listing

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