AI Article Synopsis
- The study examines the role of the APACHE II score in predicting poor outcomes in stress-induced cardiomyopathy (SIC) patients, finding it to be a significant prognostic factor.
- Out of 37 patients, primarily women with an average age of 66, a notable 16% died during hospitalization, with chest pain as the most common symptom.
- The findings suggest that a higher APACHE II score (greater than 20) is linked to an increased risk of mortality, indicating it may be more crucial than cardiac function measures for predicting outcomes in SIC patients.
Article Abstract
While the disease course of stress-induced cardiomyopathy (SIC) is usually benign, it can be fatal. The prognostic factors to predict poorer outcome are not well established, however. We analyzed the Acute Physiology And Chronic Health Evaluation (APACHE) II score to assess its value for predicting poor prognosis in patients with SIC. Thirty-seven consecutive patients with SIC were followed prospectively during their hospitalization. Clinical factors, including APACHE II score, coronary angiogram, echocardiography and cardiac enzymes at presentation were analyzed. Of the 37 patients, 27 patients (73%) were women. The mean age was 66.1 ± 15.6 yr, and the most common presentation was chest pain (38%). Initial echocardiographic left ventricular ejection fraction (EF) was 42.5% ± 9.3%, and the wall motion score index (WMSI) was 1.9 ± 0.3. Six patients (16%) expired during the follow-up period of hospitalization. Based on the analysis of characteristics and clinical factors, the only predictable variable in prognosis was APACHE II score. The patients with APACHE II score greater than 20 had tendency to expire than the others (P = 0.001). Based on present study, APACHE II score more than 20, rather than cardiac function, is associated with mortality in patients with SIC.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247775 | PMC |
| http://dx.doi.org/10.3346/jkms.2012.27.1.52 | DOI Listing |
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