Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this material to deliver doxorubicin to breast cancer cells (MCF-7). Cellular studies with MCF-7 cells showed higher uptake and cytotoxicity of doxorubicin loaded ZrP compared to free doxorubicin.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c2cc16218k | DOI Listing |
Publication Analysis
Top Keywords
zirconium phosphate
8
phosphate nano-platelets
8
doxorubicin intercalated
8
doxorubicin
5
nano-platelets novel
4
novel platform
4
platform drug
4
drug delivery
4
delivery cancer
4
cancer therapy
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!