Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury.

Genet Mol Biol

Coordenação de Recursos Pesqueiros e Agronegócio, Instituto Federal de Educação, Ciência e Tecnologia do Pará, Belém, PA, Brazil.

Published: October 2011

The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L(-1) methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229127PMC
http://dx.doi.org/10.1590/S1415-47572011000400024DOI Listing

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