Objectives: Most studies examining factors contributing to cognitive impairments and dementia in late life focused on risks. In this study, we aimed to evaluate factors that might help preserve cognition in healthy Hong Kong elders.
Methods: This was a 2-year prospective study of 476 cognitively healthy community dwellers (aged 60-92 years) recruited in Hong Kong. Participants were assessed with a battery of cognitive tests and questionnaires on their sense of loneliness and leisure activities.
Results: A high level of cognitive activity participation (r = 0.13, p = 0.03) and a low level of loneliness (r = -0.15, p = 0.01) were associated with better cognitive test performance. Participants with more years of education (odds ratio = 1.27, P < 0.001) and a higher frequency of drinking (odds ratio = 1.17, p = 0.05) were associated with high cognitive function, while those with a high level of loneliness (odds ratio = 0.79, p = 0.01) were associated with low cognitive function. The correlation with cognitive activity participation remained significant in participants with very good cognitive function (r = 0.20, p = 0.04).
Conclusions: These results suggested that social engagement and moderate drinking may be modulating factors for cognition. Further studies should explore the interactions between lifestyle factors and cognition in older adults with no significant cognitive impairment.
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iScience
January 2025
Cognitive Neuroimaging Unit, CEA, INSERM, Université Paris-Saclay, NeuroSpin Center, 91191 Gif/Yvette, France.
Recent studies showed that humans, regardless of age, education, and culture, can extract the linear trend of a noisy scatterplot. Although this capacity looks sophisticated, it may simply reflect the extraction of the principal trend of the graph, as if the cloud of dots was processed as an oriented object. To test this idea, we trained Guinea baboons to associate arbitrary shapes with the increasing or decreasing trends of noiseless and noisy scatterplots, while varying the number of points, the noise level, and the regression slope.
View Article and Find Full Text PDFFront Psychol
January 2025
Department for Clinical Psychology and Psychotherapy, Philipps University Marburg, Marburg, Germany.
Background: Several studies identified affect-regulatory qualities of deceptive placebos within negative and positive affect. However, which specific characteristics of an affect-regulatory framing impacts the placebo effect has not yet been subject to empirical investigations. In particular, it is unclear whether placebo- induced expectations of direct emotion inhibition or emotion regulation after emotion induction elicit stronger effects in affect regulation.
View Article and Find Full Text PDFRisk Manag Healthc Policy
January 2025
Department of Medical Rehabilitation Science, Faculty of Applied Medical Sciences, Umm Al-Qura University-Makkah-Saudi Arabia; Cairo University, Cairo, Egypt.
Introduction: Dual tasking (DT) requires individuals to carry out two actions simultaneously, comparable to how the brain can perform a cognitive function while the body is in motion, which eventually enhances human balance. This paper aims to examine and compare the impact of DT on the risk of falling (ROF) among Saudi female students.
Methods: A cross-sectional design was used.
EClinicalMedicine
February 2025
Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei, Anhui, China.
Background: Brain stimulation therapy (BST) has significant potential in treating psychiatric, movement, and cognitive disorders. Given the high prevalence of comorbidities among these disorders, we conducted an umbrella review to comprehensively assess the efficacy of BSTs in treating the core symptoms across these three categories of disorders.
Methods: We systematically searched for meta-analyses and network meta-analyses of randomized controlled trials with sham controls up to September 25, 2024, from databases including PubMed, PsycINFO, Embase, and the Cochrane Library.
Drug Des Devel Ther
January 2025
Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian, People's Republic of China.
Purpose: While esketamine shows promise as an adjunct in procedural sedation, its impact on postoperative cognitive recovery remains incompletely characterized. This study investigated the effects of esketamine on multiple dimensions of recovery, particularly cognition, in patients undergoing colonoscopy with propofol-based sedation.
Patients And Methods: We conducted this randomized, double-blinded, placebo-controlled trial from January 6, 2023, to May 20, 2024, at two hospitals in China.
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