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Introduction: Adrenal myelolipomas are uncommon benign adrenal tumors, which mostly occur unilaterally. We describe a rare case of giant bilateral adrenal myelolipoma mistaken for retroperitoneal liposarcoma.
Case Presentation: A 49-year-old man developed fever, left flank pain, and a large mass in his left abdomen.
Acute Tracheal Obstruction Secondary to Cervical Liposarcoma Metastasis.
Thorac Cancer
December 2024
Provincial Higher Medical College, North Sichuan Medical College, Nanchong, Sichuan Province, China.
Tracheal obstruction can arise from multiple conditions, including chronic obstructive pulmonary disease, asthma, foreign bodies, tumors, and acute heart failure. We report a case of a 43-year-old man with cervical liposarcoma who, following surgical excision, chemotherapy, and radiation, presented with severe dyspnea and was admitted to our hospital. A CT scan detected an endotracheal mass causing significant obstruction, suspected to be malignant.
View Article and Find Full Text PDFEarly Pain Relief in Malignant Psoas Syndrome with Radiation Therapy: A Case Report.
Cureus
November 2024
Radiation Oncology, Shimane University Faculty of Medicine, Izumo, JPN.
Article Synopsis
- Malignant psoas syndrome is caused by tumor infiltration of the psoas muscle, leading to severe, challenging pain management with no established definitive treatments.
- A case study of a Japanese man in his 60s showed ineffective pain relief with various medications, prompting the use of palliative radiation therapy.
- Radiation therapy effectively reduced pain early on and showed no adverse effects, suggesting it should be considered as a viable treatment option for malignant psoas syndrome.
A Very late intracardiac myxoid liposarcoma metastasis.
Eur Heart J Cardiovasc Imaging
November 2024
Department of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Plasma DNA Methylation-Based Biomarkers for MPNST Detection in Patients With Neurofibromatosis Type 1.
Mol Carcinog
January 2025
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Article Synopsis
- Malignant peripheral nerve sheath tumors (MPNSTs) show altered DNA methylation patterns, suggesting these changes could be used as specific biomarkers for NF1 patient screening.
- Researchers conducted a study involving DNA methylation profiling from tumor and adjacent tissue samples of 13 MPNST patients, finding 73 candidate CpGs that could distinguish MPNSTs from neurofibromas.
- Five validated biomarkers demonstrated high sensitivity and specificity in tissue detection, and higher methylation levels were observed in plasma tests, indicating potential for early detection of MPNST in NF1 patients.
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