Actinomycotic brain abscess and subdural empyema of odontogenic origin: case report and review of the literature.

J Oral Maxillofac Surg

Department of Oral and Maxillofacial Surgery, Louisiana State University, New Orleans, LA, USA.

Published: March 2012

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http://dx.doi.org/10.1016/j.joms.2011.09.035DOI Listing

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Article Synopsis
  • Actinomycosis is a rare, chronic infection caused by specific anaerobic bacteria, which can complicate diagnosis, especially when it affects the central nervous system.
  • A case study highlights a 29-year-old farmer with a dura-based mass that resembled a brain tumor, confirmed as actinomycosis through histopathology after surgical intervention.
  • Early diagnosis is crucial, especially in at-risk individuals, to ensure effective treatment and better recovery outcomes.
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An autopsy case of acute actinomycotic brain abscess involving a patient with rheumatoid arthritis (RA) is reported. The patient was a 72-year-old man with a seven-year history of RA and pulmonary complications, who acutely developed dysarthria and dysphagia three days before death. Autopsy revealed a fresh, non-encapsulated abscess in the "late cerebritis" stage, measuring 2 cm in diameter, in the white matter of the right parietal lobe.

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Introduction: Actinomycosis is an uncommon chronic suppurative infection that rarely affects the central nervous system (CNS). It is caused by filamentous Gram-positive anaerobic bacteria that is a normal commensal but causes suppurative and granulomatous inflammation after disruption of anatomical barriers. We report the largest series of 17 histologically confirmed cases of CNS actinomycosis and review clinical, imaging, and histopathologic features.

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Brain abscess caused by chronic invasive actinomycosis in the nasopharynx: A case report and literature review.

Medicine (Baltimore)

April 2018

Department of Otorhinolaryngology, Yonsei University Wonju College of Medicine, Wonju Department of Otorhinolaryngology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.

Article Synopsis
  • Actinomycosis is a rare bacterial infection mainly affecting the cervicofacial area and can rarely involve the central nervous system, often stemming from the Actinomyces species found in normal bodily flora.
  • A case study of a 51-year-old woman showed the development of a brain abscess 15 months after initial treatment for noninvasive nasopharyngeal actinomycosis, indicating a recurrence as an invasive form.
  • Surgical drainage combined with long-term antibiotics led to the complete resolution of the brain abscess, highlighting the importance of recognizing actinomycosis in clinical settings and its potential to mimic malignancy.
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Background: The actinomyces is germ commonly found in the normal flora of the oral cavity and gastro-intestinal and uro-genital tracts. Involvement in other locations is a very uncommon event.

Objectives: To describe a patient with an actinomicotyc brain abscess CLINICAL CASE: We report the case of a patient who suffered a seizure and decreased level of consciousness.

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