In the title compound, C(18)H(14)NSe(+)·HSO(4) (-), the cyclo-pentene ring in the cation has an envelope conformation while the central six-membered 1,4-selenazine ring adopts a sofa conformation. The dihedral angle between the planes of the terminal benzene rings is 68.08 (11)°. In the crystal, the anions form chains along the c axis through O-H⋯O hydrogen bonds. Weak C-H⋯O and C-H⋯π hydrogen bonds, as well as attractive Se⋯Se [3.5608 (8) Å] inter-actions, further consolidate the crystal structure.
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http://dx.doi.org/10.1107/S1600536811047167 | DOI Listing |
Chembiochem
December 2024
University of Minnesota, Department of Genetics, Cell Biology, and Development, MCB 5-130, 420 Washington Avenue SE, 55455, Minneapolis, UNITED STATES OF AMERICA.
RNA exhibits remarkable capacity as a functional polymer, with broader catalytic and ligand-binding capability than previously thought. Despite this, the low side chain diversity present in nucleic acids (two purines and two pyrimidines) relative to proteins (20+ side chains of varied charge, polarity, and chemical functionality) limits the capacity of functional RNAs to act as environmentally responsive polymers, as is possible for peptide-based receptors and catalysts. Here we show that incorporation of the modified nucleobase 2-thiouridine (2sU) into functional (aptamer and ribozyme) RNAs produces functionally inactivated polymers that can be activated by oxidative treatment.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Chemistry, University of Delhi-110007, New Delhi, India.
Wastewater contamination by organic dyes, especially Rhodamine B (RhB), possess a significant environmental challenge. This study explores a novel bio sorbent for the removal of RhB dye from contaminated water, using chitosan trisodium citrate-modified magnetic nanoparticles (Fe₃O₄@CSTSC@PANI) coated with polyaniline. The nanocomposite was characterized by FT-IR, XRD, HRTEM, SEM, BET surface analysis.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
December 2024
Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Significant progress has been achieved with diversity of short peptide supramolecular assemblies. However, their programmable phase modulation by single stimulus remains a great challenge. Herein, we demonstrate a dipeptide supramolecular system undergoes sequentially coupled phase transitions upon hydrogen bonding association and dissociation triggered by a single fatty acid.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
December 2024
National Engineering Research Center for Marine Aquaculture, Zhejiang Ocean University, Zhoushan, Zhejiang 316022, China.
In the study, Sargassum horneri (S. horneri) was used to create a novel zeolite-like algal biochar (KSBC). KSBC with doping of N, O, S, Al, and Si, displayed zeolite-like properties, including well-developed porosity, a high specific surface area (1137.
View Article and Find Full Text PDFBiomed Pharmacother
December 2024
Department of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:
The impairment of the p53 pathway was once regarded as inadequately druggable due to the specificity of the p53 structure, its flat surface lacking an ideal drug-binding site, and the difficulty in reinstating p53 function. However, renewed interest in p53-based therapies has emerged, with promising approaches targeting p53 and ongoing clinical trials investigating p53-based treatments across various cancers. Despite significant progress in p53-targeted therapies, challenges persist in identifying effective therapeutic targets within the p53 pathway.
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