In the title mol-ecule, C(12)H(14)N(2), the dihedral angle between the pyrazole and phenyl ring mean planes is 78.65 (19)°. In the crystal, mol-ecules are linked by N-H⋯N hydrogen bonds into chains along [010].
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238866 | PMC |
| http://dx.doi.org/10.1107/S1600536811045405 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The development of the profession and education of Prosthetics and Orthotics in South Africa.
Prosthet Orthot Int
January 2025
Department SPort Rehabilitation and Dental Science (Biokinetics Programme), Biokinetics Association of South Africa, Centurion, Gauteng, South Africa.
The history of a profession is valuable literature as it recognizes the noteworthy contributions of its forerunners and the scientific evolution from its earliest state. The purpose of this paper is to recount the historical developments in the profession of Prosthetics and Orthotics (P & O) in South Africa. An electronic literature search identified 54 Sabinet and 17,400 Google Scholar records.
View Article and Find Full Text PDFBiotechnological Perspectives on the Therapeutic Potential of Phenylpropanoid Cinnamaldehyde in Inflammatory Diseases: Signaling Pathways.
Curr Pharm Biotechnol
January 2025
Northeast Biotechnology Network - RENORBIO, Federal University of Piauí - UFPI, Teresina, Brazil.
The traditional use of plants of the Cinnamomum genus dates back to traditional Eastern medicine for millennia and they have also been used in Western integrative medicine practices, especially for their anti-inflammatory activity. In the context of chemical diversity, the absolute majority of species in this genus have cinnamaldehyde as the majority component, which in turn holds the title of the active ingredient, whose biological effect profile has already been demonstrated in numerous experiments in acute and chronic inflammatory conditions. In this context, the objective of this research was to investigate how cinnamaldehyde can influence inflammatory phenomena.
View Article and Find Full Text PDFApprehending siRNA Machinery and Gene Silencing in Brinjal Shoot and Fruit Borer, Leucinodes orbonalis.
Arch Insect Biochem Physiol
January 2025
Division of Genomic Resources, ICAR-National Bureau of Agricultural Insect Resources, Bengaluru, India.
RNA interference (RNAi) technology is widely used in gene functional studies and has been shown to be a promising next generation alternative for insect pest management. To understand the efficiency of RNAi machinery in Leucinodes orbonalis (L. orbonalis) Guenee, a destructive pest of eggplant, core RNAi pathway genes Argonaute-2, Dicer-2, Loquacious, and Sid-1 were mined from the transcriptome and characterized.
View Article and Find Full Text PDFSynthesis and antifungal activity of aldehydes-thiourea derivatives as promising antifungal agents against postharvest gray mold disease.
Chem Biodivers
January 2025
Chuxiong Normal University, Academy of Science and Technology, Chuxiong Normal University, Chuxiong, 675000，China, No. 456 Luchengnan Road, chuxiong, Academy of Science and Technology, 651000, chuxiong, CHINA.
Gray mold disease is caused by B. cinerea, which could severely reduce the production yield and quality of tomatoes. To explore more potential fungicides with new scaffolds for controlling the gray mold disease, ten aldehydes-thiourea derivatives were designed, synthesized and assayed for inhibitory activity against three plant pathogenic fungi.
View Article and Find Full Text PDFAntidiabetic agent use and clinical outcomes in patients with diabetes hospitalized for COVID-19: a systematic review and meta-analysis.
Front Endocrinol (Lausanne)
January 2025
Boston College, William F. Connell School of Nursing, Boston, MA, United States.
Background: The effect of antidiabetic agents on mortality outcomes is unclear for individuals with diabetes mellitus (DM) who are hospitalized for COVID-19.
Purpose: To examine the relationship between antidiabetic agent use and clinical outcomes in individuals with DM hospitalized for COVID-19.
Methods: A systematic review of the literature (2020-2024) was performed across five databases.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!