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Neurological and functional outcomes of 32 patients with hemorrhagic brainstem cavernous malformations: a practical guide for surgical planning.
J Neurosurg
January 2025
1Department of Neurosurgery, ASST Cremona, Italy.
Objective: Brainstem cavernous malformations (BSCMs) were once considered inoperable. Microsurgical resection now represents a valuable option for treating patients with hemorrhagic or symptomatic lesions. The aim of this study was to provide a practical guide for surgical planning by analyzing postoperative neurological and functional outcomes.
View Article and Find Full Text PDFSpectra of intracranial diseases in Chinese military pilots (cadets) unqualified for transfer to pilot modified high performance aircraft.
World J Radiol
November 2024
Naval Medical Center, Naval Medical University of Chinese PLA, Shanghai 200052, China.
Article Synopsis
- Cerebrovascular diseases and intracranial tumors pose significant risks to military pilots, emphasizing the need for thorough screening and early intervention to prevent inflight incapacitation.
- The study investigates the types of intracranial diseases and medical imaging findings in military pilots (cadets) undergoing physical exams for transfer to high performance aircraft, aiming to improve aeromedical support.
- Of 554 pilots examined, 36 were found with abnormal MRI results, displaying conditions such as arachnoid cysts, small aneurysms, and other issues that disqualified them from flying high-performance aircraft.
Implementation of high-definition fiber tractography for preoperative evaluation and surgical planning of brainstem cavernous malformation: long-term outcomes.
J Neurosurg
November 2024
Departments of1Neurological Surgery and.
Objective: The aim of this study was to describe the role and long-term outcomes of high-definition fiber tractography (HDFT) in the surgical management of brainstem cavernomas.
Methods: The authors performed a retrospective evaluation of their database at the HDFT laboratory in a single academic institution.
Results: The authors identified 11 patients with brainstem cavernomas who had HDFT for preoperative workup and underwent microsurgical resection.
Intraparenchymal Chordoma in the Brain Stem: A Review of Surgical Management and Case Highlight.
Cureus
August 2024
Neurological Surgery, University of Miami Miller School of Medicine, Miami, USA.
We present a rare case of an intraparenchymal chordoma in the brain stem of a 69-year-old male with a history of multiple chordoma recurrences. Chordomas are uncommon tumors that originate from notochordal remnants, with intraparenchymal presentations in the brain stem being particularly rare. A 69-year-old male with a history of clival chordoma three years after primary endoscopic resection and adjuvant proton-beam radiotherapy and a recurrence one year postoperatively for which he underwent a second surgery, presented with severe headaches, weakness, diaphoresis, and difficulty ambulating.
View Article and Find Full Text PDFDemystifying the Mystery of Genes: A Case Report on Constitutional Mismatch Repair Deficiency.
Indian J Radiol Imaging
July 2024
Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.
Constitutional mismatch repair deficiency (CMMRD) is a rare childhood cancer predisposition syndrome that results from biallelic germline mutations in one of the four MMR genes, MLH1, MSH2, MSH6, or PMS2. This syndrome is characterized by a broad spectrum of early-onset malignancies, including hematologic malignancies, colorectal malignancies, brain tumors, and other malignancies. It is common to have more than one malignancy in an individual diagnosed with CMMRD.
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