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The Indian journey of assisted reproductive therapy began in Calcutta on 3 October 1978, when Dr Subhas Mukhopadhyay discovered the technique of in vitro fertilisation (IVF) only 67 days following the birth of the world's first IVF baby, Louise Brown in the United Kingdom by Edwards and Steptoe. While Edwards won the Nobel Prize in 2010 for his groundbreaking work, Mukhopadhyay, the man behind the genesis of 'Durga', India's first IVF baby, never received any recognition. Instead, he faced severe humiliation from his peers.

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Objective: Evaluation of the development of assisted reproduction methods and their success from the time of their origin to the present.

Design: Review article.

Setting: Department of Obstetrics and Gynaecology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague.

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This writing presents personal reflections on issues raised by the recent publication of texts concerning the developing story of infertility treatment since the delivery of Louise Brown in 1978. It is written by a woman whose own natural conception coincided with the commencement of Steptoe and Edwards's collaboration, and who herself received, as an adult, a treatment to which their work gave rise. It addresses itself to the as yet mostly anonymous and silent female subjects-the self-styled 'Ovum Club'-without whose involvement in the original research programme in Oldham in 1969-1978 Louise would never have been born, to be followed by millions of in vitro fertilisation (IVF) babies worldwide.

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