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Detecting the factors associated with financial decision-making is an unresolved challenge when trying to predict digital financial behavior. This paper reports experimental results on both neuropsychological and neuronal correlates of risk-taking and betrayal aversion among 121 healthy participants (X=21.7; SD = 2.

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Do Novel Nonexercise and Nondrug Treatments Improve Global Cognition in Parkinson's Disease Patients? A Systematic Review and Bayesian Analysis.

Eur J Neurosci

February 2025

Department of Neurology, Guangdong Neuroscience Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

This Bayesian network meta-analysis method was used to assess the effect of novel treatments on global cognition in patients with Parkinson's disease (PD). We searched randomized controlled trials from PubMed, Cochrane Library, Web of Science and Embase to investigate novel treatments for global PD cognition until April 10, 2024. Effect size measures were standardized mean differences with 95% confidence intervals.

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Biomarker treatment effects in two phase 3 trials of gantenerumab.

Alzheimers Dement

January 2025

Department of Radiology & Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.

Introduction: We report biomarker treatment effects in the GRADUATE I and II phase 3 studies of gantenerumab in early Alzheimer's disease (AD).

Methods: Amyloid and tau positron emission tomography (PET), volumetric magnetic resonance imaging (vMRI), cerebrospinal fluid (CSF), and plasma biomarkers used to assess gantenerumab treatment related changes on neuropathology, neurodegeneration, and neuroinflammation over 116 weeks.

Results: Gantenerumab reduced amyloid PET load, CSF biomarkers of amyloid beta (Aβ)40, total tau (t-tau), phosphorylated tau 181 (p-tau181), neurogranin, S100 calcium-binding protein B (S100B), neurofilament light (NfL), alpha-synuclein (α-syn), neuronal pentraxin-2 (NPTX2), and plasma biomarkers of t-tau, p-tau181, p-tau217, and glial fibrillary acidic protein (GFAP) while increasing plasma Aβ40, Aβ42.

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Objective: To evaluate the effectiveness of a treatment complex including magnetophoresis with the drug «Argensept» and tear therapy in patients with mild to moderate dry eye syndrome.

Material And Methods: The study was conducted on 50 people (100 eyes) diagnosed with mild to moderate dry eye syndrome (H04.1 according to ICD-10).

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Objective: To evaluate the efficiency of treatment complexes based on magnetic-laser therapy with electrical stimulation and dry salt baths in the rehabilitation treatment of patients with chronic prostatitis.

Material And Methods: There have been observed 74 men with chronic abacterial prostatitis at the age of 34-46 years old. The patients were divided into groups using the simple randomization method depending on the therapy.

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