This article presents the basic principles of the superstimulated echo mechanism and shows preliminary results of its application to T1-weighted imaging with positive T1-contrast. A superstimulated echo scheme uses a preparation of square-wave modulated, periodically inverted z-magnetization, which after signal evolution during the mixing time TM is fully converted into transverse magnetization. This avoids the 50% signal loss of a conventional stimulated echo. Furthermore, its implementation as a preparation module for standard turbo spin echo (TSE) imaging allows producing images with positive T1-contrast.
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http://dx.doi.org/10.1002/mrm.24111 | DOI Listing |
Korean J Radiol
April 2024
Department of Radiology, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.
Objective: To develop and evaluate a deep learning model for automated segmentation and detection of bone metastasis on spinal MRI.
Materials And Methods: We included whole spine MRI scans of adult patients with bone metastasis: 662 MRI series from 302 patients (63.5 ± 11.
ACS Appl Mater Interfaces
February 2024
Nanomaterials for Biomedical Applications, Istituto Italiano di Tecnologia, 16163 Genova, Italy.
In this work, we constructed a multifunctional composite nanostructure for combined magnetic hyperthermia therapy and magnetic resonance imaging based on and signals. First, iron oxide nanocubes with a benchmark heating efficiency for magnetic hyperthermia were assembled within an amphiphilic polymer to form magnetic nanobeads. Next, poly(acrylic acid)-coated inorganic sodium gadolinium fluoride nanoparticles were electrostatically loaded onto the magnetic nanobead surface via a layer-by-layer approach by employing a positively charged enzymatic-cleavable biopolymer.
View Article and Find Full Text PDFActa Biomater
January 2024
Department of Radiology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, 12 Wulumuqi Middle Road, Shanghai 200040, China; National Center for Neurological Disorders, 12 Wulumuqi Middle Road, Shanghai 200040, China. Electronic address:
Epilepsy refers to a disabling neurological disorder featured by the long-term and unpredictable occurrence of seizures owing to abnormal excessive neuronal electrical activity and is closely linked to unresolved inflammation, oxidative stress, and hypoxia. The difficulty of accurate localization and targeted drug delivery to the lesion hinders the effective treatment of this disease. The locally activated inflammatory cells in the epileptogenic region offer a new opportunity for drug delivery to the lesion.
View Article and Find Full Text PDFCancers (Basel)
January 2023
Department of Neuro-Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
(1) Introduction and objective: Surgical resection plays an important role in the multidisciplinary treatment of lung cancer patients with brain metastases (BMs). Precisely distinguishing the tumor border intraoperatively to improve and maximize the extent of resection (EOR) without causing permanent neurological defects is crucial but still challenging. Therefore, we introduced our experience of utilizing sodium fluorescein (SF) in microneurosurgery of BMs from lung cancer.
View Article and Find Full Text PDFBiomed Phys Eng Express
November 2022
Queensland University of Technology, Australia.
. To explore the efficacy of two different approaches to train a Fully Convolutional Neural Network (FCNN) with Graphical Processing Unit (GPU) memory limitations and investigate if pre-trained two-dimensional weights can be transferred into a three-dimensional model for the purpose of brain tumour segmentation..
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