We present a case of fever, brain abscesses, and Gemella morbillorum bacteremia after anti-tumor necrosis factor alpha (TNF-α) therapy in a 21-year-old acne inversa patient currently taking long-term dapsone. To the best of our knowledge, this is the first report describing such a case. During antimicrobial therapy, the patient developed systemic varicella infection with severe thrombocytopenia.
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http://dx.doi.org/10.1128/JCM.06161-11 | DOI Listing |
Vascular
December 2024
Department of Vascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
Objectives: Ruptured mycotic pseudoaneurysms are rare, yet devastating complications that can prove challenging to manage. In immunocompromised populations, highly virulent organisms such as Gemella morbillorum can be especially difficult to combat. Here, we outline our approach to temporizing maneuvers in an emergent setting and definitive revascularization in a 27-year-old with a ruptured mycotic iliac artery pseudoaneurysm from necrosis of her kidney and pancreas allografts.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
October 2024
Ospedale Santa Maria della Misericordia di Udine Endocrinology Unit Udine Italy.
Background: Acute suppurative thyroiditis (AST) is a rare form of thyroid inflammation prevalently of bacterial origin, that usually affects subjects with risk factors such as immunodeficiency, sepsis, and neck fistulas. The most prevalent pathogens associated with AST are gram-positive aerobic bacteria, followed by gram-negatives, while infections by anaerobic germs are exceptionally rare. Gemella morbillorum is a facultative anaerobic gram-positive bacterium that commonly populates the upper respiratory tract.
View Article and Find Full Text PDFBMC Infect Dis
November 2024
Guangzhou Red Cross Hospital of Jinan University, Guangzhou, Guangdong, 510220, China.
Gemella morbillorum is a gram-positive coccus that is part of the normal microbiota of the human oral cavity and gastrointestinal tract. It is an opportunistic pathogen that can cause invasive infections, including septic arthritis. Septic arthritis caused by Gemella morbillorum is relatively rare, but when it occurs, it can lead to severe joint damage and other complications if not promptly diagnosed and treated.
View Article and Find Full Text PDFS Afr Med J
November 2024
Department of Orthopaedics, Steve Biko Academic Hospital, Pretoria, South Africa.
Pyogenic spondylodiscitis is an uncommon but important clinical condition that often requires medical and/or surgical management. We report a case of spondylodiscitis caused by a rare pathogen, Gemella morbillorum. To date, worldwide, only six such cases of confirmed spondylodiscitis infection with this rare pathogen have been documented, and this is the first reported case in South Africa.
View Article and Find Full Text PDFInfect Drug Resist
October 2024
Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, Gansu, 730030, People's Republic of China.
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