Finite element (FE) modelling is a popular tool for studying human body response to blast exposure. However, blast modelling is a complex problem owing to more numerous fluid-structure interactions (FSIs) and the high-frequency loading that accompanies blast exposures. This study investigates FE mesh design for blast modelling using a sphere in a closed-ended shock tube meshed with varying element sizes using both tetrahedral and hexahedral elements. FSI was consistent for sphere-to-fluid element ratios between 0.25 and 4, and acceleration response was similar for both element types (R(2) = 0.997). Tetrahedral elements were found to become increasingly volatile following shock loading, causing higher pressures and stresses than predicted with the hexahedral elements. Deviatoric stress response was dependent on the sphere mesh size (p < 0.001), while the pressure response was dependent on the shock tube mesh size (p < 0.001). The results of this study highlight the necessity for mesh sensitivity analysis in blast models.
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http://dx.doi.org/10.1080/10255842.2011.629615 | DOI Listing |
Commun Biol
January 2025
Institute of Phytopathology, Research Centre for BioSystems, Land Use and Nutrition, Justus Liebig University Giessen, Heinrich-Buff-Ring 26, 35392, Giessen, Germany.
In vertebrates and plants, dsRNA plays crucial roles as PAMP and as a mediator of RNAi. How higher fungi respond to dsRNA is not known. We demonstrate that Magnaporthe oryzae (Mo), a globally significant crop pathogen, internalizes dsRNA across a broad size range of 21 to about 3000 bp.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Department of Civil Engineering, Engineering Faculty, Firat University, 23100 Elazig, Türkiye.
In this study, the usability of construction and demolition waste (CDW) aggregates as filling when stabilized with alkaline activator solution (AAS) and blast furnace slag (BFS) was investigated. The initial stage of this study involved determining the engineering properties of CDW by laboratory experiments. In the next stage, modified Proctor tests were performed to investigate the compaction behavior of CDW, to which 5% to 30% BFS was added with water or AAS.
View Article and Find Full Text PDFEur J Trauma Emerg Surg
January 2025
Department of Military Traffic Injury Prevention and Control, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Introduction: While there is evidence supporting the use of ultrasound for real-time monitoring of primary blast lung injury (PBLI), uncertainties remain regarding the timely detection of early PBLI and the limited data correlating it with commonly used clinical parameters. Our objective is to develop a functional incapacity model for PBLI that better addresses practical needs and to verify the early diagnostic effectiveness of lung ultrasound in identifying PBLI.
Methods: We selected six healthy male pigs to develop an animal model using a bio-shock tube (BST-I).
Neurobiol Pain
December 2024
Virginia Polytechnic Institute and State University. Department of Biomedical Engineering, 325 Stranger St., Blacksburg, VA 24060, United States.
Chronic headaches and pain are prevalent in those who are exposure to blast events, yet there is a gap in fundamental data that identifies the pathological mechanism for the chronification of pain. Blast-related post-traumatic headaches (PTH) are understudied and chronic pain behaviors in preclinical models can be vital to help elucidate PTH mechanisms. The descending pain modulatory system controls pain perception and involves specific brain regions such as the cortex, thalamus, pons, and medulla.
View Article and Find Full Text PDFJ Affect Disord
January 2025
King's Centre for Military Health Research, King's College London, SE5 9RJ, United Kingdom of Great Britain and Northern Ireland; Academic Department of Military Mental Health, King's College London, SE5 9RJ, United Kingdom of Great Britain and Northern Ireland.
Background: Heart rate variability (HRV) is governed by sympathetic and parasympathetic regulatory systems. Post-Traumatic Stress Disorder (PTSD) may influence these systems and consequently affect cardiovascular functioning.
Methods: The sample consisted of 860 UK male military personnel approximately half of whom had sustained physical combat injuries in Afghanistan.
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