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NON-INVASIVE METHOD OF MONITORING INTRACRANIAL PRESSURE FOR THE EVALUATION OF HEPATIC ENCEPHALOPATHY.
Arq Gastroenterol
November 2024
Faculdade de Medicina de São José do Rio Preto, Departamento de Cardiologia e Cirurgia Cardiovascular, São José do Rio Preto, São Paulo , Brasil.
Article Synopsis
- The study investigates a new non-invasive method for monitoring intracranial pressure (ICP) in patients with liver diseases and hepatic encephalopathy (HE), aiming to provide an alternative to invasive techniques.
- It uses a specific equipment, Brain4Care® BWS, to analyze ICP pulse morphology and correlates it with clinical signs of HE, focusing on key peaks that indicate intracranial compliance.
- Results show significant differences in ICP patterns between patients with and without HE, highlighting the method's potential for effective monitoring and assessment in clinical settings.
Exposure to Molybdate Results in Metabolic Disorder: An Integrated Study of the Urine Elementome and Serum Metabolome in Mice.
Toxics
April 2024
State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
The increasing use of molybdate has raised concerns about its potential toxicity in humans. However, the potential toxicity of molybdate under the current level of human exposure remains largely unknown. Endogenous metabolic alterations that are caused in humans by environmental exposure to pollutants are associated with the occurrence and progression of many diseases.
View Article and Find Full Text PDFDevelopment of Notch-Free, Pre-Bent Rod Applicable for Posterior Corrective Surgery of Thoracolumbar/Lumbar Adolescent Idiopathic Scoliosis.
J Clin Med
September 2023
Department of Orthopaedic Surgery, Hokkaido University Hospital, N15W7, Sapporo 060-8638, Hokkaido, Japan.
Adolescent idiopathic scoliosis (AIS), the most common pediatric musculoskeletal disorder, causes a three-dimensional spine deformity. Lenke type 5 AIS is defined as a structural thoracolumbar/lumbar curve with nonstructural thoracic curves. Although a rod curvature will affect clinical outcomes, intraoperative contouring of the straight rod depends on the surgeon's knowledge and experience.
View Article and Find Full Text PDFSalidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Inflamm Res
June 2022
Department of Cell Biology and Medical Genetics, School of Basic Medical Sciences, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Objective: Salidroside (SAL) is a marker glycoside of Rhodiola rosea with significant antioxidant, anti-inflammatory, and other health benefits. In this study, we determined its neuroprotective effects against Cd-induced toxicity in cultured cells and mice.
Materials And Methods: GL261 cell and Cd-intoxicated mouse model were used.
Why don't ventricles dilate in pseudotumor cerebri? A circuit model of the cerebral windkessel.
J Neurosurg Pediatr
June 2022
1Department of Neurological Surgery, Stony Brook University Renaissance School of Medicine, Stony Brook, New York; and.
Objective: Pseudotumor cerebri is a disorder of intracranial dynamics characterized by elevated intracranial pressure (ICP) and chronic cerebral venous hypertension without structural abnormalities. A perplexing feature of pseudotumor is the absence of the ventriculomegaly found in obstructive hydrocephalus, although both diseases are associated with increased resistance to cerebrospinal fluid (CSF) resorption. Traditionally, the pathophysiology of ventricular dilation and obstructive hydrocephalus has been attributed to the backup of CSF due to impaired absorption, and it is unclear why backup of CSF with resulting ventriculomegaly would not occur in pseudotumor.
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