Purpose: Limited information is available regarding the normal range of mesopic sine wave contrast sensitivity (CS). The aim of this study was therefore to define a reference range and in addition to identify factors related to mesopic CS in a young population.
Methods: Individuals with normal visual acuity (VA) were included from a population of air crew members visiting the Institute of Aviation Medicine for routine medical examinations. CS was measured using the Optec 6500/FACT and evaluated by (i) the CS curve with five frequencies and (ii) the index of contrast sensitivity (ICS). ICS was defined as the sum of the weighted differences from the median CS value for each frequency. Multivariate analyses were performed to identify factors related to CS.
Results: In a total of 197 subjects included, the mean mesopic CS score was significantly lower compared to the corresponding photopic measurements for all five frequencies tested. Median CS score for frequencies 1.5, 3, 6, 12 and 18 cycles per degree was 50, 114, 180, 60 and 33 for photopic and 71, 80, 90, 22 and 12 for mesopic (- glare) conditions, respectively. Better binocular VA was positively associated, while the use of corrective lenses was negatively associated with CS performance.
Conclusion: We have provided reference values for mesopic CS and identified factors important for CS. The difference between mesopic and photopic measurements highlights the need for separate population norms. The new ICS score may be a useful collective descriptor of the traditional CS curve with five frequencies.
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http://dx.doi.org/10.1111/j.1755-3768.2011.02323.x | DOI Listing |
Acta Ophthalmol
January 2025
Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Purpose: To explore the potential correlation between subjective and measured visual function, as well as to analyse the influence of eye disease, socioeconomic factors and emotional dimensions.
Methods: Semi-structured interviews, physical examinations and functional tests (n = 1203). Demographics covered sex, marital status, education, household economy, smoking and alcohol.
Interv Neuroradiol
January 2025
Department on Stroke Medicine and Vascular Neurology, North Bristol NHS Trust, Bristol, UK.
Background: Early identification and quantification of core infarct is of importance in stroke management for treatment selection, prognostication, and complication prediction. Non-contrast computed tomography (CT) (NCCT) remains the primary tool, but it suffers from limited sensitivity and inter-rater variability; CT perfusion is inconsistently available and commonly blighted by movement artefact. We assessed the performance of a standardised form of CT angiographic source imaging (CTASI) obtained through addition of a delayed phase at 40 seconds post-contrast injection (DP40) following fast-acquisition CT angiography.
View Article and Find Full Text PDFCurr Med Imaging
January 2025
Department of Intensive Care Unit, Huzhou Third Municipal Hospital, The Affiliated Hospital of Huzhou University, Huzhou, Zhejiang Province 313000, China.
Objective: This study aimed to explore the diagnostic value of multiorgan (heart, lungs, blood vessels) point-of-care ultrasound (PoCUS) in patients with high-risk and medium-to-low-risk pulmonary embolism (PE).
Methods: Clinical data of 92 patients with suspected PE, admitted to Hangzhou TCM Hospital affiliated with Zhejiang Chinese Medical University from July 2021 to June 2023, were retrospectively analyzed. According to hemodynamic status, patients were divided into the high-risk (n=28) and the medium-to-low-risk groups (n=64).
Plant Biol (Stuttg)
January 2025
Department of Behavioral Physiology and Sociobiology, University of Würzburg, Würzburg, Germany.
Nature offers a bewildering diversity of flower colours. Understanding the ecology and evolution of this fantastic floral diversity requires knowledge about the visual systems of their natural observers, such as insect pollinators. The key question is how flower colour and pattern can be measured and represented to characterise the signals that are relevant to pollinators.
View Article and Find Full Text PDFBiochimie
January 2025
Jagiellonian University Medical College, Faculty of Health Sciences, Department of Medical Physiology, Chair of Biomedical Sciences, 12 Michalowskiego st., 33-332 Cracow, Poland.
Obesity treatment requires an individualized approach, emphasizing the need to identify metabolic pathways of diagnostic relevance. Toll-like receptors (TLRs), particularly TLR2 and TLR4, play a crucial role in metabolic disorders, as receptor deficiencies improves insulin sensitivity and reduces obesity-related inflammation. Additionally, hydrogen sulfide (HS) influences lipolysis, adipogenesis, and adipose tissue browning through persulfidation.
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