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Aberrant acetylation caused by a CDYL splicing mutation contributes to thin mid-piece related asthenoteratozoospermia and male infertility.
Andrology
January 2025
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Objectives: Acetylated tubulin is a hallmark of flagellar stability in spermatozoa, and studies have demonstrated the ability of CDYL to function as a tubulin acetyltransferase in spermatozoa. Of note, germline conditional knockout of Cdyl can lead to asthenoteratozoospermia and infertility in male mice. However, the role of CDYL gene in human fertility remains uncharacterized.
View Article and Find Full Text PDFPreparation and characterization of a rat uterine decellularized scaffold.
Gland Surg
December 2024
Department of Gynecology, Wenzhou People's Hospital, Wenzhou, China.
Background: Infertility is a special reproductive health defect. For women, congenital uterine malformations, extensive adhesions in the uterine cavity, and hysterectomy are associated with infertility. Uterine transplantation is technically feasible, but its clinical application and development are limited by donor shortages and immune rejection.
View Article and Find Full Text PDFNutritional effects of invasive macrophyte detritus on infections in snail intermediate hosts.
Hydrobiologia
September 2022
Department of Biology, Emory University, Atlanta, GA USA 30322.
Schistosomes are parasitic flatworms that cycle between humans and freshwater snails, infecting more than 200 million humans. Many schistosome-endemic sites are invaded by non-native plants that snails cannot consume. Inedible plants could suppress snail growth, reproduction, and schistosome production by outcompeting edible resources.
View Article and Find Full Text PDFOxytocin enhances creativity specifically in approach-motivated individuals.
Soc Cogn Affect Neurosci
January 2025
School of Psychology, Central China Normal University, Wuhan 430079, China.
Oxytocin, a neuropeptide pivotal in social and reproductive behaviors, has recently gained attention for its potential impact on cognitive processes relevant to creativity. Yet, the direct intricate interplay between oxytocin and creativity, particularly in the context of individual differences in motivational orientations, remains poorly understood. Here, we investigated the effects of intranasal oxytocin on creative thinking in individuals characterized by varying levels of approach and avoidance motivations.
View Article and Find Full Text PDFChanges in Support for Advance Provision and Over-the-Counter Access to Medication Abortion.
JAMA Netw Open
January 2025
Advancing New Standards in Reproductive Health, University of California, San Francisco, Oakland.
Importance: Since Dobbs v Jackson Women's Health Organization (Dobbs) removed federal abortion protections, people's views about alternative models of abortion care may have been impacted, yet research on this topic is limited.
Objective: To examine changes in national support for and personal interest in advance provision (AP) and over-the-counter (OTC) access to medication abortion.
Design, Setting, And Participants: Two nationally representative cross-sectional online surveys were administered to a market research firm's panel members who were assigned female at birth (AFAB) and aged 15 to 49 years from December 2021 to January 2022 (before Dobbs) and June to July 2023 (after Dobbs).
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