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Technical Advances Drive the Molecular Understanding of Effectors from Wheat and Barley Powdery Mildew Fungi.
Mol Plant Microbe Interact
January 2025
University of Cologne, Institute for Plant Sciences, Cologne, Germany.
Pathogens manipulate host physiology through the secretion of virulence factors (effectors) to invade and proliferate on the host. The molecular functions of effectors inside plant hosts have been of interest in the field of molecular plant-microbe interactions. Obligate biotrophic pathogens, such as rusts and powdery mildews, cannot proliferate outside of plant hosts.
View Article and Find Full Text PDFSarcopenic obesity and brain health: A critical appraisal of the current evidence.
Nutr Bull
January 2025
Curtin School of Population Health, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia.
Sarcopenic obesity (SO) is a body composition phenotype derived from the simultaneous presence in the same individual of an increase in fat mass and a decrease in skeletal muscle mass and/or function. Several protocols for the diagnosis of SO have been proposed in the last two decades making prevalence and disease risk estimates of SO heterogeneous and challenging to interpret. Dementia is a complex neurological disorder that significantly impacts patients, carers and healthcare systems.
View Article and Find Full Text PDFAtropine plus omeprazole for acute gastritis: Efficacy and safety analysis.
Pak J Pharm Sci
January 2025
Jian'ou Municipal Hospital, Nanping, Fujian, China.
Article Synopsis
- The article evaluates the effectiveness and safety of a combination treatment of atropine (ATR) and omeprazole (OME) for acute gastritis (AG) in comparison to anisodamine (ADM) with OME.
- The study involved 95 patients, with the ATR+OME group showing a higher success rate, fewer side effects, and quicker symptom relief than the ADM+OME group.
- Results indicated that the ATR+OME treatment significantly reduced inflammatory markers and gastrointestinal hormone levels, suggesting its strong efficacy and safety for managing AG, making it suitable for wider clinical use.
[A Review of progresses in research on delayed resistance to EGFR-TKI by Traditional Chinese medicine via inhibiting cancer stem cells properties].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2025
Department of Integrated Traditional Chinese and Western Medicine, Shandong First Medical University Affiliated Cancer Hospital, Jinan 250117, China. *Corresponding author, E-mail:
It has been popular and challenging to undertake researches on the delay of acquired resistance of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI). As key cells for tumor initiation, cancer stem cells (CSC) play an important role in the process of resistance to EGFR-TKI. Although preliminary studies found that traditional Chinese medicine (TCM) could inhibit CSC properties and delay EGFR-TKI resistance, the specific molecular mechanism remains unclear.
View Article and Find Full Text PDFModified Green-Ampt model for infiltration analysis in loess area and its parameter determination and verification.
Sci Rep
January 2025
School of Civil Engineering, Chang'an University, Xi'an, 710061, China.
Water infiltration into soil is important in geotechnical engineering. The classical Green-Ampt (GA) infiltration model is widely used in soil infiltration due to its physical significance, but it ignores the actual unsaturated layer in the infiltration process and has some deficiencies. Thus, the present study established a modified GA infiltration model (MLGA model) using Darcy's infiltration law and continuity equation to fully consider the variation characteristics of the soil water profile in the infiltration process.
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