Objective: The present study investigated the efficacy of a biphasic calcium phosphate as a bone grafting material for maxillary sinus augmentation in humans.
Materials And Methods: Half of the thirty patients selected for sinus augmentation were grafted with biphasic calcium phosphate, whereas the other half were grafted with autogenous bone chips harvested intraorally. After 9 months of healing, bone cores were retrieved from implant sites for histologic and histomorphometric evaluation.
Results: The areas augmented with autogenous bone chips showed newly formed bone with a pattern very similar to that of the native area. Histomorphometry demonstrated that the amount of newly formed bone in the autogenous bone group was significantly greater than in the biphasic calcium phosphate group (P < 0.05). In the biphasic calcium phosphate group, less bone formation was observed in the area further away from native bone interface than in the area closer to native bone interface (P < 0.05), whereas no significant differences were observed between both areas in the autogenous group. In both groups, the implant survival rate was 100% with a minimum 1-year follow-up.
Conclusion: The data presented in this work confirm the osteoconductive properties of biphasic calcium phosphate, as well as its use in association with maxillary sinus floor augmentation procedures with successful outcomes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1600-0501.2011.02384.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Smart core-shell microneedles for psoriasis therapy: In situ self-assembly of calcium ion-coordinated dexamethasone hydrogel.
J Control Release
January 2025
State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs, College of Pharmacy, Jinan University, Guangzhou 511443, China. Electronic address:
Psoriasis is a prevalent relapsing dermatological condition that often necessitates lifelong treatment. The distinctive thickening of the stratum corneum presents a challenge to drug penetration. The employment of microneedles has been demonstrated to enhance the transdermal drug delivery efficacy by creating multiple microchannels in the skin.
View Article and Find Full Text PDFSuccessful treatment of a C2 aneurysmal bone cyst with hydroxyapatite and calcium sulfate synthetic bone void filler injection: a case report.
J Spine Surg
December 2024
Department of Neurosurgery, The Gemelli University Hospital, Rome, Italy.
Background: Aneurysmal bone cysts (ABCs) are benign, blood-filled neoplasms causing bone destruction, often requiring resection. However, challenges arise, especially at the cranio-cervical junction, where proximity to critical structures limits removal. Non-surgical options include selective arterial embolization (SAE) as main treatment, while Denosumab and centrifugated bone marrow emerge as experimental alternatives.
View Article and Find Full Text PDFOptimized synthesis of biphasic calcium phosphate: enhancing bone regeneration with a tailored β-tricalcium phosphate/hydroxyapatite ratio.
Biomater Sci
January 2025
Institute of Chemical Technology, Vietnam Academy of Science and Technology, 1A TL29 Street, Thanh Loc Ward, District 12, Ho Chi Minh City 700000, Vietnam.
Biphasic calcium phosphate (BCP) is a bioceramic widely used in hard tissue engineering for bone replacement. BCP consists of β-tricalcium phosphate (β-TCP) - a highly soluble and resorbable phase - and hydroxyapatite (HA) - a highly stable phase, creating a balance between solubility and resorption, optimally supporting cell interactions and tissue growth. The β-TCP/HA ratio significantly affects the resorption, solubility, and cellular response, with a higher β-TCP ratio increasing resorption due to its solubility.
View Article and Find Full Text PDFDevelopment of Bioinspired Biphasic Calcium Phosphate Inks for Manufacturing Bone Scaffolds by Robocasting.
3D Print Addit Manuf
October 2024
New Technologies Research Center, Amirkabir University of Technology, Tehran, Iran.
Robocasting calcium phosphate compounds as a novel approach to creating customized structures with interconnected pores not only overcomes the limitations of traditional fabrication methods of calcium phosphate substitutes but also boosts the potential for bone tissue regeneration. The ink development is a key step in 3D printing. In this study, different inks consisting of magnesium- and sodium-doped carbonated hydroxyapatite, β-tricalcium phosphate, and Pluronic F-127 were prepared to design biomimetic bone scaffolds.
View Article and Find Full Text PDFEnhancing bone regeneration through 3D printed biphasic calcium phosphate scaffolds featuring graded pore sizes.
Bioact Mater
April 2025
Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
Human long bones exhibit pore size gradients with small pores in the exterior cortical bone and large pores in the interior cancellous bone. However, most current bone tissue engineering (BTE) scaffolds only have homogeneous porous structures that do not resemble the graded architectures of natural bones. Pore-size graded (PSG) scaffolds are attractive for BTE since they can provide biomimicking porous structures that may lead to enhanced bone tissue regeneration.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!