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Evaluation of ketorolac ceiling dose effects in pediatric patients in the emergency department.
Am J Emerg Med
December 2024
Department of Pharmacy, Children's Hospital Colorado, Aurora, CO, United States of America.
Background: The use of ketorolac for analgesia in the emergency department is a common practice for pediatric patients. There is a lack of guidance on optimal dosing to limit the risk of side effects especially in pediatric patients. The standard dosing is weight based with a cap at 30 mg, a dose which is higher than the typical max used for adult patients.
View Article and Find Full Text PDFGreen Fabrication of Silver Nanoparticles, Statistical Process Optimization, Characterization, and Molecular Docking Analysis of Their Antimicrobial Activities onto Cotton Fabrics.
J Funct Biomater
November 2024
Botany Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
Nanotechnological methods for creating multifunctional fabrics are attracting global interest. The incorporation of nanoparticles in the field of textiles enables the creation of multifunctional textiles exhibiting UV irradiation protection, antimicrobial properties, self-cleaning properties and photocatalytic. Nanomaterials-loaded textiles have many innovative applications in pharmaceuticals, sports, military the textile industry etc.
View Article and Find Full Text PDFSynergistic Optimization of Buried Interface via Hydrochloric Acid for Efficient and Stable Perovskite Solar Cells.
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December 2024
State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources, School of New Energy, North China Electric Power University, Beijing, 102206, China.
Incorporating chlorine into the SnO electron transport layer (ETL) has proven effective in enhancing the interfacial contact between SnO and perovskite in perovskite solar cells (PSCs). However, previous studies have primarily focused on the role of chlorine in passivating surface trap defects in SnO, without considering its influence on the buried interface. Here, hydrochloric acid (HCl) is introduced as a chlorine source into commercial SnO to form Cl-capped SnO (Cl-SnO) ETL, aiming to optimize the buried interface of the PSC.
View Article and Find Full Text PDFCurcumin-Modified Selenium Nanoparticles Improve S180 Tumour Therapy in Mice by Regulating the Gut Microbiota and Chemotherapy.
Int J Nanomedicine
December 2024
School of Life Science and Medicine, Shandong University of Technology, Zibo, 255000, People's Republic of China.
Purpose: This study aimed to synthesize curcumin-modified selenium (Cur/Se) nanoparticles via a simple and green method for tumour treatment and explore their effects on the gut microbiota.
Methods: Curcumin was applied as a reducing and capping agent for the construction of Cur/Se nanoparticles with Tween 80 as a stabilizer. The drug release behaviour and DPPH and ABTS radical scavenging activities of the Cur/Se nanoparticles were detected.
Green-synthesized α-FeO-nanoparticles as potent antibacterial, anti-biofilm and anti-virulence agent against pathogenic bacteria.
BMC Microbiol
December 2024
Department of Physics, College of Science, University of Halabja, Halabja, Kurdistan Region, Iraq.
Background: Antimicrobial resistance (AMR) presents a serious threat to health, highlighting the urgent need for more effective antimicrobial agents with innovative mechanisms of action. Nanotechnology offers promising solutions by enabling the creation of nanoparticles (NPs) with antibacterial properties. This study aimed to explore the antibacterial, anti-biofilm, and anti-virulence effects of eco-friendly synthesized α-Fe₂O₃ nanoparticles (α-Fe₂O₃-NPs) against pathogenic bacteria.
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