Using steps in the Iowa Model of Evidence-Based Practice, nursing staff developed and piloted a standardized shift report tool on one medical-surgical unit in a large tertiary care hospital. Pilot outcomes showed shift reports with decreased frequency of missed information, fewer delays in shift starting time, and less use of overtime.
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EClinicalMedicine
February 2025
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.
Unlabelled: Non-communicable diseases (NCDs) characterised by type 2 inflammation, including asthma, allergic rhinitis, chronic rhinosinusitis with nasal polyps, atopic dermatitis, food allergies and eosinophilic esophagitis, are increasing in prevalence worldwide. Currently, there is a major paradigm shift in the management of these diseases, towards the concept of disease modification and the treatment goal remission, regardless of severity and age. Remission as a treatment goal in chronic inflammatory NCDs was first introduced in rheumatoid arthritis, and then adopted in other non-type 2 inflammatory diseases.
View Article and Find Full Text PDFFoot Ankle Orthop
January 2025
Department of Surgery, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.
Background: The outcome of a secondary subtalar arthrodesis after prior calcaneal fracture has been widely described. However, the surgical treatment has evolved significantly over the past decade, paralleling the shifts observed in primary repair strategies. Therefore, we describe the outcome following a secondary arthrodesis after an intra-articular calcaneal fracture, comparing the in situ (ISA) and bone block distraction arthrodesis (BBDA) techniques.
View Article and Find Full Text PDFFood Chem X
January 2025
Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi 110012, India.
The accurate quantification of glycemic index (GI) remains crucial for diabetes management, yet current methodologies are constrained by resource intensiveness and methodological limitations. digestion models face challenges in replicating the dynamic conditions of the human gastrointestinal tract, such as enzyme variability and multi-time point analysis, leading to suboptimal predictive accuracy. This review proposes an integrated technological framework combining non-enzymatic electrochemical sensing with artificial intelligence to revolutionize GI assessment.
View Article and Find Full Text PDFIndiana Univ J Undergrad Res
June 2024
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine.
Angiomotins (Amots) are a family of adaptor proteins with important roles in cell growth, migration, and proliferation. The Amot coiled-coil homology (ACCH) domain has a high affinity for non-phosphorylated and mono-phosphorylated phosphatidylinositol which provides specificity in the membrane association. The membrane specificity is linked with targeting and recycling of the membrane protein to maintain normal cell phenotypes and function.
View Article and Find Full Text PDFMater Today Bio
February 2025
The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Developing disease models and screening for effective drugs are key areas of modern medical research. Traditional methodologies frequently fall short in precisely replicating the intricate architecture of bodily tissues and organs. Nevertheless, recent advancements in biomaterial-assisted organoid technology have ushered in a paradigm shift in biomedical research.
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