This paper is part 10 of a historical article on young students from Hyuga who went to Osaka or Kyoto to study in the Edo period. The article investigates the influence of these students on medical and pharmaceutical sciences in the Hyuga, which is now Miyazaki-Prefecture. The knowledge in this area is limited, thus, we aimed to examine and summarize the historical events. It was found that seven students, Bunchu Niizuma, Shikan Kai, Kaneo Niizuma, Ritsukei Shiraishi, Bunkichi Maki, Genzou Katayose and Buntetsu Kai, studied under Sanyou Rai in Osaka, and two students, Zusho Hayakawa and Chikanaga Nyuta-Motonaka, studied under Toyou Yamawaki in Kyoto. Both Kaneo Niizuma and Zusho Hayakawa participated in the foundation of the medical school called "Meidou-kan" at Nobeoka in 1857 before the Meiji Restoration in 1868.
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