The adaptation of techniques of molecular genetic analysis into clinical practice increased the possibilities of diagnostics of urinary bladder cancer at early stage of disease development. The article discusses the results of cytological and cytogenetic examination of urine cells in patients with diagnostics of urinary bladder cancer. The sampling consisted of 44 cytological and 25 cytogenetic tests. The results of both methods of diagnostics of urinary bladder cancer matched in 12 cases. Besides, in 2 tests the carcinoma of urinary bladder was confirmed only by using molecular genetic technique.

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